Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

Glutathione (GSH) is a tripeptide, which has many biological roles including protection
against reactive oxygen and nitrogen species. The primary goal of this paper is to …

Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

Several epidemiologic studies have shown that diets rich in fruits and vegetables reduce the
risk of developing several chronic diseases, such as type 2 diabetes, atherosclerosis, and …

Arginine is a conditionally essential amino acid. To elucidate the influence of l-arginine on
the activation of endogenous antioxidant defence, male Wistar rats were orally administered …

Organisms are constantly exposed to a broad range of pathological and stress-inducing
agents, allergens and environmental chemicals that can induce infections, toxicity or other …

The recent search for new anti-cancer drugs focuses more on natural compounds from the
regular human diet because these compounds rarely exhibit severe side-effects yet …

Cisplatin is massively used to treat solid tumors. However, several severe adverse effects,
such as cardiotoxicity, are obstacles to its clinical application. Cardiotoxicity may lead to …

The nuclear factor E2-related factor 2 (Nrf2) plays an important role in cellular protection
against cancer, renal, pulmonary, cardiovascular and neurodegenerative diseases where …