Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry

MM Gomari, N Saraygord-Afshari, M Farsimadan… - Biotechnology …, 2020 - Elsevier
Tag-assisted protein purification is a method of choice for both academic researches and
large-scale industrial demands. Application of the purification tags in the protein production …

Regulation of choroid plexus development and its functions

P Kompaníková, V Bryja - Cellular and Molecular Life Sciences, 2022 - Springer
The choroid plexus (ChP) is an extensively vascularized tissue that protrudes into the brain
ventricular system of all vertebrates. This highly specialized structure, consisting of the …

Cerebrospinal fluid pH regulation

HH Damkier, J Praetorius - Pflügers Archiv-European Journal of …, 2024 - Springer
The cerebrospinal fluid (CSF) fills the brain ventricles and the subarachnoid space
surrounding the brain and spinal cord. The fluid compartment of the brain ventricles …

Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

CSJ Westgate, C Kamp‐Jensen… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Diseases of raised intracranial pressure (ICP) cause
severe morbidity and mortality. Multiple drugs are utilised to lower ICP including …

Characterization of the microRNA transcriptomes and proteomics of cochlear tissue-derived small extracellular vesicles from mice of different ages after birth

P Jiang, X Ma, S Han, L Ma, J Ai, L Wu, Y Zhang… - Cellular and Molecular …, 2022 - Springer
The cochlea is an important sensory organ for both balance and sound perception, and the
formation of the cochlea is a complex developmental process. The development of the …

[HTML][HTML] Biallelic variants in SLC4A10 encoding a sodium-dependent bicarbonate transporter lead to a neurodevelopmental disorder

R Maroofian, M Zamani, R Kaiyrzhanov, L Liebmann… - Genetics in …, 2024 - Elsevier
Purpose SLC4A10 encodes a plasma membrane-bound transporter, which mediates Na+-
dependent HCO 3− import, thus mediating net acid extrusion. Slc4a10 knockout mice show …

Targeting choroid plexus epithelium as a novel therapeutic strategy for hydrocephalus

Y Yang, J He, Y Wang, C Wang, C Tan, J Liao… - Journal of …, 2022 - Springer
The choroid plexus is a tissue located in the lateral ventricles of the brain and is composed
mainly of choroid plexus epithelium cells. The main function is currently thought to be the …

A systems-level analysis of bile acids effects on rat colon epithelial cells

J Yde, Q Wu, JF Borg, RA Fenton… - American Journal of …, 2022 - journals.physiology.org
Bile acid diarrhea is a chronic condition caused by increased delivery of bile acids to the
colon. The underlying mechanisms remain to be elucidated. To investigate genes involved …

Understanding and Modeling the Pathophysiology of Hydrocephalus: In Search of Better Treatment Options

V Newland, LL Jantzie, BL Blazer-Yost - Physiologia, 2024 - mdpi.com
Hydrocephalus is caused by an overproduction of cerebrospinal fluid (CSF), an obstruction
of fluid movement, or improper reabsorption. CSF accumulation in the brain's ventricles …

Multiple Na, K-ATPase subunits colocalize in the brush border of mouse choroid plexus epithelial cells

I Baasch Christensen, L Cheng, JR Brewer… - International journal of …, 2021 - mdpi.com
(1) Background: The unusual accumulation of Na, K-ATPase complexes in the brush border
membrane of choroid plexus epithelial cells have intrigued researchers for decades …