Flavoenzymes are colourful oxidoreductases that catalyze a large variety of different types of
reactions. Flavoenzymes have been extensively studied for their structural and mechanistic …

Many enzymes use one or more cofactors, such as biotin, heme, or flavin. These cofactors
may be bound to the enzyme in a noncovalent or covalent manner. Although most …

Monensin A is a prototypical natural polyether polyketide antibiotic. It acts by binding a metal
cation and facilitating its transport across the cell membrane. Biosynthesis of monensin A …

Highlights•Enzyme-catalyzed linking of carbohydrates and aliphats as bio-based
surfactants.•Enzymatic functionalization of carbohydrates for click chemistry.•Enzymatic …

Carbohydrates are widely abundant molecules present in a variety of forms. For their
biosynthesis and modification, nature has evolved a plethora of carbohydrate-acting …

Understanding how flavin-dependent enzymes activate oxygen for their oxidation and
oxygenation reactions is one of the most challenging issues in flavoenzymology. Density …

Enzymes in the glucose–methanol–choline (GMC) oxidoreductase superfamily catalyze the
oxidation of an alcohol moiety to the corresponding aldehyde. In this review, the current …

Alcohols are a rich source of compounds from renewable sources, but they have to be
activated in order to allow the modification of their carbon backbone. The latter can be …

C-glycosides are natural products with important biological activities but are recalcitrant to
degradation. Glycoside 3-oxidases (G3Oxs) are recently identified bacterial flavo-oxidases …

This work describes for the first time the identification of a reaction intermediate, C4a-
hydroperoxyflavin, during the oxidative half-reaction of a flavoprotein oxidase, pyranose 2 …