[HTML][HTML] A current overview of RhoA, RhoB, and RhoC functions in vascular biology and pathology

R Eckenstaler, M Hauke, RA Benndorf - Biochemical Pharmacology, 2022 - Elsevier
The Rho subfamily members of Rho GTPases, RhoA, RhoB, and RhoC, are key regulators
of signal transduction in a variety of cellular processes, including regulation of actomyosin …

Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …

Expression analysis of Rho GTPase-related lncRNAs in breast cancer

A Nicknam, SK Pour, MA Hashemnejad… - … -Research and Practice, 2023 - Elsevier
Abstract The Rho GTPases have prominent roles in cell cycle transition and cell migration.
Some members of this family have been found to be mutated in cancers. Moreover …

Co-Expression Network Analysis Unveiled lncRNA-mRNA Links Correlated to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance and/or …

V Fustaino, G Papoff, F Ruberti, G Ruberti - International Journal of …, 2024 - mdpi.com
We investigated mRNA-lncRNA co-expression patterns in a cellular model system of non-
small cell lung cancer (NSCLC) sensitive and resistant to the epithelial growth factor …

LncRNAs and regulated cell death in tumor cells

Y Wu, X Wen, Y Xia, X Yu, Y Lou - Frontiers in Oncology, 2023 - frontiersin.org
Regulated Cell Death (RCD) is a mode of cell death that occurs through drug or genetic
intervention. The regulation of RCDs is one of the significant reasons for the long survival …

A lncRNA MALAT1 is a positive regulator of RhoA protein expression in bronchial smooth muscle cells

Y Chiba, Y Adachi, Y Ando, S Fujii, W Suto, H Sakai - Life Sciences, 2023 - Elsevier
Aims Augmented smooth muscle contractility of the airways associated with an increased
expression of RhoA, a monomeric GTPase responsible for Ca 2+ sensitization of …

Diallyl disulfide downregulating RhoGDI2 induces differentiation and inhibit invasion via the Rac1/Pak1/LIMK1 pathway in human leukemia HL‐60 cells

T Hui, J Yiling, C Guangqun, L Ran, L Hui… - Environmental …, 2023 - Wiley Online Library
Leukemia is a type of disease in which hematopoietic stem cells proliferate clonally at the
genetic level. We discovered previously by high‐resolution mass spectrometry that diallyl …

Clinical significance of lncRNA XIST expression in cholangiocarcinoma and its effect on cell migration and invasion

C Li, Y Dong, Y Zhang, C Wu - Clinics and Research in Hepatology and …, 2024 - Elsevier
Background Cholangiocarcinoma is a malignant tumor that occurs in the bile duct system,
and the prognosis of patients is poor. Currently, research suggests that long non-coding …

MCM3AP-AS1: A LncRNA participating in the tumorigenesis of cancer through multiple pathways

B Wang, J Chen, C Lin, R Liu, L Wang… - Mini Reviews in …, 2022 - ingentaconnect.com
Background: More and more shreds of evidence show that the occurrence and development
of tumors are closely related to the abnormal expression of LncRNA. A large number of …

Construction and analysis of the CDKN2B-AS1 ceRNA network associated with KRAS-dependent tumorigenesis in colorectal and pancreatic cancer

M Saliani, A Javadmanesh, P Gonbadi, S Rahimi… - 2024 - researchsquare.com
Kirsten rat sarcoma viral oncogene homolog (KRAS) exhibits the highest mutation rate in
colorectal cancer (CRC) and pancreatic cancer (PC), highlighting the need for a …