West Nile virus (WNV) is a positive-stranded RNA virus belonging to the Flaviviridae family,
a large family with 3 main genera (flavivirus, hepacivirus and pestivirus). Among these …

West Nile virus (WNV) is a widely spread human pathogenic arthropod-borne virus. It can
lead to severe, sometimes fatal, neurological disease. Over the last two decades, several …

Zika virus (ZIKV) infection during pregnancy has emerged as a global public health problem
because of its ability to cause severe congenital disease. Here, we developed six mouse …

West Nile virus (WNV) is a neurotropic, arthropod-borne flavivirus that is maintained in an
enzootic cycle between mosquitoes and birds, but can also infect and cause disease in …

Flaviviruses cause a spectrum of potentially severe diseases. Most flaviviruses are
transmitted by mosquitoes or ticks and are widely distributed all over the world. Among them …

Background Since its first appearance in the USA in 1999, West Nile virus (WNV) has
spread in the Western hemisphere and continues to represent an important public health …

West Nile encephalitis emerged in 1999 in the United States, then rapidly spread through
the North American continent causing severe disease in human and horses. Since then …

Background Dengue viruses (DENVs) and Japanese encephalitis virus (JEV) have
significant cross-reactivity in serological assays; the clinical implications of this remain …

Advax is a polysaccharide-based adjuvant that potently stimulates vaccine immunogenicity
without the increased reactogenicity seen with other adjuvants. This study investigated the …

The flavivirus envelope glycoprotein (E) is responsible for viral attachment and entry by
membrane fusion. Its ectodomain is the primary target of the humoral immune response. In …