Pimaricin (natamycin) is a small polyene macrolide antibiotic used worldwide. This efficient
antimycotic and antiprotozoal agent, produced by several soil bacterial species of the genus …

Chagas disease is one of the most important public health problems in Latin America due to
its high mortality and morbidity levels. There is no effective treatment for this disease since …

The aim of this study was to evaluate the chemical profile and antioxidant, antimicrobial and
antiparasitic activities of the hydroalcoholic extract of the leaves of Ziziphus joazeiro …

Chagas disease (CD) is a parasitic zoonosis endemic in Central and South America
affecting nearly 10 million people, with 100 million people at high risk of contracting the …

Polyene macrolides are potent antifungal agents that are also active against parasites,
enveloped viruses and prion diseases. They are medically important as antifungal …

Background Chagas disease is one of the most important public health problems and a
leading cause of cardiac failure in Latin America. The currently available drugs to treat T …

Chagas disease or American Trypanosomiasis, a parasitic infection typically spread by
triatomine bugs, affects millions of people throughout Latin America. Current chemotherapy …

The species Cordia verbenacea DC (Boraginaceae), known as the whaling herb and
camaradinha, is a perennial shrub species native to the Atlantic Forest. Its leaves are used …

Chagas disease is caused by Trypanosoma cruzi, being considered a public health
problem. An alternative to combat this pathogen is the use of natural products isolated from …

The polyene macrolide group includes important antifungal drugs, to which resistance does
not arise readily. Chemical and biological methods have been used in attempts to make …