Advances in Spheroids and Organoids on a Chip
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …
medicine and drug screening. They replicate the structural and functional characteristics of …
Osteogenic differentiation of MSC through calcium signaling activation: transcriptomics and functional analysis
F Viti, M Landini, A Mezzelani, L Petecchia, L Milanesi… - PloS one, 2016 - journals.plos.org
The culture of progenitor mesenchymal stem cells (MSC) onto osteoconductive materials to
induce a proper osteogenic differentiation and mineralized matrix regeneration represents a …
induce a proper osteogenic differentiation and mineralized matrix regeneration represents a …
Micropattern-controlled chirality of focal adhesions regulates the cytoskeletal arrangement and gene transfection of mesenchymal stem cells
Cell chirality has been demonstrated to be important for controlling cell functions. However,
it is not clear how the chirality of the extracellular microenvironment regulates cell adhesion …
it is not clear how the chirality of the extracellular microenvironment regulates cell adhesion …
The varied influences of cell adhesion and spreading on gene transfection of mesenchymal stem cells on a micropatterned substrate
Transmembrane transport of exogenous genes is widely investigated because of high
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …
Influence of cell spreading area on the osteogenic commitment and phenotype maintenance of mesenchymal stem cells
Osteogenic differentiation and commitment of mesenchymal stem cells (MSCs) is a complex
process that is induced and regulated by various biological factors and biophysical cues …
process that is induced and regulated by various biological factors and biophysical cues …
Regulation of gene transfection by cell size, shape and elongation on micropatterned surfaces
Gene transfection has been widely studied due to its potential applications in tissue repair
and gene therapy. Many studies have focused on designing gene carriers and developing …
and gene therapy. Many studies have focused on designing gene carriers and developing …
Matrix-assisted pulsed laser methods for biofabrication
Controlling the spatial arrangement of biomaterials, including living cells, with high
resolution (±5 μm) provides the foundation for fabricating complex biologic systems for …
resolution (±5 μm) provides the foundation for fabricating complex biologic systems for …
Regulation of mesenchymal stem cell functions by micro–nano hybrid patterned surfaces
Micro-and nano-structured substrates have been widely used in the biomedical engineering
field. Their precise control of cell morphology makes them promising for investigating …
field. Their precise control of cell morphology makes them promising for investigating …
Maintaining the pluripotency of mouse embryonic stem cells on gold nanoparticle layers with nanoscale but not microscale surface roughness
Z Lyu, H Wang, Y Wang, K Ding, H Liu, L Yuan, X Shi… - Nanoscale, 2014 - pubs.rsc.org
Efficient control of the self-renewal and pluripotency maintenance of embryonic stem cell
(ESC) is a prerequisite for translating stem cell technologies to clinical applications. Surface …
(ESC) is a prerequisite for translating stem cell technologies to clinical applications. Surface …
Osseointegration enhancement by controlling dispersion state of carbonate apatite in polylactic acid implant
C Zhang, K Hayashi, K Ishikawa - Colloids and Surfaces B: Biointerfaces, 2023 - Elsevier
Osteoconductive ceramics (OCs) are often used to endow polylactic acid (PLA) with
osseointegration ability. Conventionally, OC powder is dispersed in PLA. However …
osseointegration ability. Conventionally, OC powder is dispersed in PLA. However …