Organoarsenicals in seafood: occurrence, dietary exposure, toxicity, and risk assessment considerations–A review

C Luvonga, CA Rimmer, LL Yu… - Journal of agricultural and …, 2020 - ACS Publications
Diet, especially seafood, is the main source of arsenic exposure for humans. The total
arsenic content of a diet offers inadequate information for assessment of the toxicological …

Metabolism and toxicity of arsenicals in mammals

A Sattar, S Xie, MA Hafeez, X Wang, HI Hussain… - Environmental …, 2016 - Elsevier
Arsenic (As) is a metalloid usually found in organic and inorganic forms with different
oxidation states, while inorganic form (arsenite As-III and arsenate As-v) is considered to be …

Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing

B Moe, H Peng, X Lu, B Chen, LWL Chen… - Journal of …, 2016 - Elsevier
The occurrence of a large number of diverse arsenic species in the environment and in
biological systems makes it important to compare their relative toxicity. The toxicity of arsenic …

Comparative evaluation of in vivo relative bioavailability and in vitro bioaccessibility of arsenic in leafy vegetables and its implication in human exposure assessment

X Zheng, Z Zhang, J Chen, H Liang, X Chen… - Journal of Hazardous …, 2022 - Elsevier
Arsenic (As) contamination in vegetables is a severe threat to human health. However, the
evaluation of As relative bioavailability (As-RBA) or bioaccessibility in vegetables is still …

Arsenic Metabolism by Human Gut Microbiota upon in Vitro Digestion of Contaminated Soils

T Van de Wiele, CM Gallawa… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Speciation analysis is essential when evaluating risks from arsenic (As)
exposure. In an oral exposure scenario, the importance of presystemic metabolism by gut …

The risk of arsenic induced skin lesions in Bangladeshi men and women is affected by arsenic metabolism and the age at first exposure

AL Lindberg, M Rahman, LÅ Persson… - Toxicology and applied …, 2008 - Elsevier
It is known that a high fraction of methylarsonate (MA) in urine is a risk modifying factor for
several arsenic induced health effects, including skin lesions, and that men are more …

Disruption of the arsenic (+ 3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention …

Z Drobna, H Naranmandura… - Chemical research in …, 2009 - ACS Publications
The arsenic (+ 3 oxidation state) methyltransferase (As3mt) gene encodes a 43 kDa protein
that catalyzes methylation of inorganic arsenic. Altered expression of AS3MT in cultured …

Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells

H Naranmandura, MW Carew, S Xu, J Lee… - Chemical research in …, 2011 - ACS Publications
The human bladder is one of the primary target organs for arsenic-induced carcinogenicity,
and arsenic metabolites in urine have been suspected to be directly involved in …

Biotransformation of arsenic and toxicological implication of arsenic metabolites

S Hirano - Archives of toxicology, 2020 - Springer
Arsenic is a well-known environmental carcinogen and chronic exposure to arsenic through
drinking water has been reported to cause skin, bladder and lung cancers, with arsenic …

Arsenic metabolism and thioarsenicals

K Rehman, H Naranmandura - Metallomics, 2012 - academic.oup.com
Arsenic has received considerable attention in the world, since it can lead to a multitude of
toxic effects and has been recognized as a human carcinogen causing cancers. Here, we …