Objectives: We undertook the review of all available cases of hypersensitivity reactions after
placement of a drug-eluting stent (DES) and classified potential causes. Background: Six …

What is known and objective The off‐label use of medicines is widespread in several
diseases. This type of prescribing practice is particularly more acute in oncology. However …

Rituximab improves outcomes for persons with lymphoproliferative disorders and is
increasingly used to treat immune-mediated illnesses. Recent reports describe 2 patients …

Background Recently, increasing numbers of women receiving adjuvant chemotherapy for
breast cancer have also received granulocyte colony-stimulating factors (G-CSFs) or …

Over the past several months clinicians have been con-fronted at an escalating rate with
reports describing the risks of COX-2 inhibitors (coxibs). Information on this class of drugs …

Zygomycosis is increasingly reported as a cause of life-threatening fungal infections. A
higher proportion of cases reported over the last decades have been in cancer patients, with …

Comparative effectiveness reviews (CERs) are systematic reviews that evaluate evidence
on alternative interventions to help clinicians, policy makers, and patients make informed …

Purpose–Medical device users are one of the principal medical device technology
stakeholders. The involvement of users in medical device technology development and …

Background: In the United States, hip fracture rates have declined by 30% coincident with
bisphosphonate use. However, bisphosphonates are associated with sporadic cases of …

Background Treatment of latent tuberculosis infection (LTBI) is an important aspect of
tuberculosis control in the United States, but the effectiveness of this strategy is …