Chemotherapy based on repeated doses of praziquantel remains the most effective control
strategy against schistosomiasis, a neglected tropical disease caused by platyhelminths of …

In search of antiparasitic agents, we here identify arylmethylamino steroids as potent
compounds and characterize more than 60 derivatives. The lead compound 1o is fast acting …

Schistosomiasis is a neglected disease of poverty that is caused by several species of the
trematode flatworm, Schistosoma. Treatment relies on just one drug, the …

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Introduction: The risk of drug resistance and the use of medicinal plants in malaria …

Scrophularia genus belonging to the family of Scrophulariaceae, is a medicinal plant widely
distributed in Iran. In the present study, the anti-malarial activity of different extracts of three …

From the organic extracts of the sponge Siphonochalina fortis, collected at Bahía
Bustamante, Chubut, Argentina, three major compounds were isolated and identified as …

Oximation of 20-hydroxyecdysone oxo derivatives proceeds regio-and stereoselectively and
provides (E)-configured oximes in quantitative yields. The Ni–Ra-catalyzed hydrogenation of …

Objective: To assess the in vivo antimalarial potential of various solvent extracts and
fractions of Trema orientalis. Methods: In this study, the animal model of antimalarial activity …

A method for the synthesis of two (23 R)-and (23 S)-epimeric pairs of 23-fluoro-3α, 7α, 12α-
trihydroxy-5β-cholan-24-oic acid and 23-fluoro-3α, 7α-dihydroxy-5β-cholan-24-oic acid is …

We report an improved synthesis of the (22R)‐and (22S)‐epimers of 3α, 7α, 12α, 22‐
tetrahydroxy‐5β‐cholan‐24‐oic acid and 3α, 7α, 22‐trihydroxy‐5β‐cholan‐24‐oic acid from …