Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis

S Kumar, Q Duan, R Wu, EN Harris, Q Su - Advanced drug delivery reviews, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that encompasses a
spectrum of pathological conditions, ranging from simple steatosis (NAFL), nonalcoholic …

Mitochondrial dysfunction and signaling in chronic liver diseases

A Mansouri, CH Gattolliat, T Asselah - Gastroenterology, 2018 - Elsevier
Mitochondria regulate hepatic lipid metabolism and oxidative stress. Ultrastructural
mitochondrial lesions, altered mitochondrial dynamics, decreased activity of respiratory …

Review of cadmium toxicity effects on fish: Oxidative stress and immune responses

JW Lee, AH Jo, DC Lee, CY Choi, JC Kang… - Environmental research, 2023 - Elsevier
Cadmium (Cd) in aquatic environments can cause environmental toxicity to fish and induce
oxidative stress owing to an excessive production of reactive oxygen species in fish bodies …

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

PA Williams, JM Harder, NE Foxworth, KE Cochran… - Science, 2017 - science.org
Glaucomas are neurodegenerative diseases that cause vision loss, especially in the elderly.
The mechanisms initiating glaucoma and driving neuronal vulnerability during normal aging …

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

V Hung, SS Lam, ND Udeshi, T Svinkina, G Guzman… - elife, 2017 - elifesciences.org
The cytosol-facing membranes of cellular organelles contain proteins that enable signal
transduction, regulation of morphology and trafficking, protein import and export, and other …

[HTML][HTML] Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor γ …

Z He, X Li, Z Wang, Y Cao, S Han, N Li, J Cai, S Cheng… - Redox Biology, 2023 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the
deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in …

Nuclear-mitochondrial interactions

BR Walker, CT Moraes - Biomolecules, 2022 - mdpi.com
Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Nanoplastics promote arsenic-induced ROS accumulation, mitochondrial damage and disturbances in neurotransmitter metabolism of zebrafish (Danio rerio)

C Zhang, Y Li, H Yu, L Ye, T Li, X Zhang… - Science of the Total …, 2023 - Elsevier
As a carrier, nanoplastics (NPs) can adsorb other toxic substances and thus modify their
biological toxicity. Numerous studies have investigated the neurotoxic of high concentrations …

[HTML][HTML] The role of mitochondria in sepsis-induced cardiomyopathy

G Stanzani, MR Duchen, M Singer - … Acta (BBA)-Molecular Basis of Disease, 2019 - Elsevier
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. Myocardial dysfunction, often termed sepsis-induced cardiomyopathy …

[HTML][HTML] Drp1 promotes KRas-driven metabolic changes to drive pancreatic tumor growth

S Nagdas, JA Kashatus, A Nascimento, SS Hussain… - Cell reports, 2019 - cell.com
Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the
dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRas G12V …