Mortality from severe dengue is low, but the economic and resource burden on health
services remains substantial in endemic settings. Unfortunately, progress towards …

Dengue is the most rapidly spreading mosquito-borne disease and has become a major
public health threat, particularly for tropical and subtropical countries including Bangladesh …

The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …

Background Aedes aegypti mosquitoes infected with the w Mel strain of Wolbachia pipientis
are less susceptible than wild-type A. aegypti to dengue virus infection. Methods We …

The recent emergence and re-emergence of viral infections transmitted by vectors—Zika,
chikungunya, dengue, Japanese encephalitis, West Nile, yellow fever and others—is a …

Dengue, caused by four closely related viruses, is a growing global public health concern,
with outbreaks capable of overwhelming health-care systems and disrupting economies …

Background: Ae. aegypti mosquitoes stably transfected with the intracellular bacterium
Wolbachia pipientis (wMel strain) have been deployed for biocontrol of dengue and related …

The burden of dengue is large and growing. More than half of the global population lives in
areas with risk of dengue transmission. Uncertainty in burden estimates, however …

Background Large Phase III trials across Asia and Latin America have recently
demonstrated the efficacy of a recombinant, live-attenuated dengue vaccine (Dengvaxia) …

Summary The Strategic Advisory Group of Experts (SAGE) on Immunization advises WHO
on global policies for vaccines. In April, 2016, SAGE issued recommendations on the use of …