Steroid avoidance or withdrawal for kidney transplant recipients

MC Haller, A Royuela, EV Nagler… - Cochrane Database …, 2016 - cochranelibrary.com
Background Steroid‐sparing strategies have been attempted in recent decades to avoid
morbidity from long‐term steroid intake among kidney transplant recipients. Previous …

[HTML][HTML] A systematic review of conversion from calcineurin inhibitor to mammalian target of rapamycin inhibitors for maintenance immunosuppression in kidney …

WH Lim, J Eris, J Kanellis, B Pussell, Z Wiid… - American Journal of …, 2014 - Elsevier
This was a systematic review of randomized controlled trials comparing delayed conversion
of mammalian target of rapamycin inhibitors (mTORi) for calcineurin inhibitors (CNIs) versus …

Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature

B Nashan, F Citterio - Transplantation, 2012 - journals.lww.com
Surgical complications, including events such as lymphocele and urological complications
that affect wound healing, are reported with an incidence of 15% to 32% after kidney …

Novel sirolimus–coated balloon catheter: In vivo evaluation in a porcine coronary model

YP Clever, D Peters, J Calisse, S Bettink… - Circulation …, 2016 - Am Heart Assoc
Background—Limus-eluting stents are dominating coronary interventions, although
paclitaxel is the only drug on balloon catheters with proven inhibition of restenosis …

Molecular pathways and therapies in autosomal-dominant polycystic kidney disease

T Saigusa, PD Bell - Physiology, 2015 - journals.physiology.org
Autosomal-dominant polycystic kidney disease (ADPKD) is the most prevalent inherited
renal disease, characterized by multiple cysts that can eventually lead to kidney failure …

Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model

T Jones-Hughes, T Snowsill, M Haasova… - Health Technology …, 2016 - discovery.ucl.ac.uk
BACKGROUND: End-stage renal disease is a long-term irreversible decline in kidney
function requiring renal replacement therapy: kidney transplantation, haemodialysis or …

[HTML][HTML] Defining the role of sirolimus in the management of graft-versus-host disease: from prophylaxis to treatment

A Abouelnasr, J Roy, S Cohen, T Kiss… - Biology of Blood and …, 2013 - Elsevier
Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after
allogeneic hematopoietic stem cell transplantation (HSCT). Measures developed that have …

[HTML][HTML] Five-year results of a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation: the SPIESSER study

Y Lebranchu, R Snanoudj, O Toupance… - American Journal of …, 2012 - Elsevier
Calcineurin inhibitors improve acute rejection rates and short-term graft survival in renal
transplantation, but their continuous use may be deleterious. We evaluated the 5-year …

The evolution of donation after circulatory death renal transplantation: a decade of experience

R Bell, S Farid, S Pandanaboyana… - Nephrology Dialysis …, 2019 - academic.oup.com
Background This study compared long-term outcomes of renal transplantation from donors
following donation after circulatory death (DCD) with those following donation after brain …

Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational …

M Schleuning, D Judith, Z Jedlickova, T Stübig… - Bone marrow …, 2009 - nature.com
Certain leukemias have a high relapse risk even after allo-SCT, and GVHD prophylaxis with
calcineurin inhibitors (CNIs) may interfere with a possible GVL effect. Therefore, we replaced …