Lost in time: Relocating the perception of duration outside the brain

D Robbe - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
It is well-accepted in neuroscience that animals process time internally to estimate the
duration of intervals lasting between one and several seconds. More than 100 years ago …

Revisiting the effect of nicotine on interval timing

CW Daniels, E Watterson, R Garcia, GJ Mazur… - Behavioural brain …, 2015 - Elsevier
This paper reviews the evidence for nicotine-induced acceleration of the internal clock when
timing in the seconds-to-minutes timescale, and proposes an alternative explanation to this …

The isolation of motivational, motoric, and schedule effects on operant performance: a modeling approach

RJ Brackney, THC Cheung… - Journal of the …, 2011 - Wiley Online Library
Dissociating motoric and motivational effects of pharmacological manipulations on operant
behavior is a substantial challenge. To address this problem, we applied a response‐bout …

Sex differences in the timing behavior performance of 3xTg-AD and wild-type mice in the peak interval procedure

E Gür, E Fertan, F Kosel, AA Wong, F Balcı… - Behavioural Brain …, 2019 - Elsevier
We investigated interval timing behavior of 10-month-old male and female 3xTg-AD mice
compared with their B6129F2/J wild type controls using the peak interval procedure with a …

Interval timing under a behavioral microscope: Dissociating motivational and timing processes in fixed-interval performance

CW Daniels, F Sanabria - Learning & behavior, 2017 - Springer
The distribution of latencies and interresponse times (IRTs) of rats was compared between
two fixed-interval (FI) schedules of food reinforcement (FI 30 s and FI 90 s), and between two …

Beyond single discrete responses: An integrative and multidimensional analysis of behavioral dynamics assisted by Machine Learning

A León, V Hernandez, J Lopez, I Guzman… - Frontiers in behavioral …, 2021 - frontiersin.org
Understanding behavioral systems as emergent systems comprising the environment and
organism subsystems, include spatial dynamics as a primary dimension in natural settings …

Quinpirole-induced sensitization to noisy/sparse periodic input: temporal synchronization as a component of obsessive-compulsive disorder

BM Gu, RK Cheng, B Yin, WH Meck - Neuroscience, 2011 - Elsevier
Quinpirole-sensitized rats were tested on a discrete-trials 40-s peak-interval procedure
using lever pressing as the instrumental response. Although there was no evidence of …

Assessment of the 'timing'function of schedule-induced behavior on fixed-interval performance.

GE López-Tolsa, R Pellón - Journal of Experimental Psychology …, 2021 - psycnet.apa.org
It has been suggested that schedule-induced behaviors allow organisms to adapt better to
temporal regularities of the environment. The main goal of the present study was to observe …

Interval timing deficits and their neurobiological correlates in aging mice

E Gür, YA Duyan, S Arkan, A Karson, F Balcı - Neurobiology of Aging, 2020 - Elsevier
Age-related neurobiological and cognitive alterations suggest that interval timing (as a
related function) is also altered in aging, which can, in turn, disrupt timing-dependent …

Interval‐timing Protocols and Their Relevancy to the Study of Temporal Cognition and Neurobehavioral Genetics

B Yin, NA Lusk, WH Meck - Handbook of neurobehavioral …, 2017 - Wiley Online Library
Humans and other animals can be shown to process temporal information as if they use an
internal stopwatch that can be “run”,“paused”, and “reset” on command and whose speed of …