Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Osteosarcoma Osteosarcoma, which is most common in people 10 to 30 years of age, is
generally treated with resection and adjuvant chemotherapy. Detection of gene …

Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-
sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic …

Highlights•This Clinical Practice Guideline provides key recommendations on the
management of bone sarcomas.•Recommendations have been agreed following a …

Background Osteosarcoma is the most common primary bone malignancy. As a rare cancer,
population‐based studies remain small with limited information on finer demographic …

Ceramic bone implants have potential properties ideal for long-term implantation
applications. On comparison with other materials, ceramic biomaterials have advantages …

Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …

Osteosarcoma is the most common primary bone sarcoma and is often diagnosed in the 2nd–
3rd decades of life. Response to the aggressive and highly toxic neoadjuvant methotrexate …

Purpose EF24, a synthetic analogue of curcumin, was developed as an anti-tumor
compound to induce apoptosis, inhibit proliferation and metastasis in various cancers …

The rising concerns of the recurrence and bone deficiency in surgical treatment of malignant
bone tumors have raised an urgent need of the advance of multifunctional therapeutic …