Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which
affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing …

Uncontrolled inflammation is a leading cause of many clinically relevant diseases. Current
therapeutic strategies focus mainly on immunosuppression rather than on the mechanisms …

Pemphigus vulgaris is a chronic autoimmune bullous dermatosis that results from the
production of autoantibodies against desmogleins 1 and 3. It is the most frequent and most …

Pemphigus is an epidemiologically heterogeneous group of autoimmune bullous diseases
comprising pemphigus vulgaris (PV), pemphigus foliaceus, paraneoplastic pemphigus, IgA …

Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated
by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins …

Autoimmune bullous disorders are a heterogeneous spectrum of skin disorders
characterized by the production of autoantibodies against adhesion molecules of the skin …

Background Pemphigus vulgaris and pemphigus foliaceus are potentially life‐threatening
autoimmune disorders triggered by IgG autoantibodies against mucosal and epidermal …

Background Cases of severe autoimmune blistering diseases (AIBDs) have recently been
reported in association with the severe acute respiratory syndrome coronavirus 2 (SARS …

Background Rituximab and mycophenolate mofetil are used to treat pemphigus vulgaris, but
they have not been adequately compared in clinical trials. Methods In a randomized …

Bruton's tyrosine kinase (BTK), a member of the Tec kinase family, is critically involved in a
range of immunological pathways. The clinical application of BTK inhibitors for B‐cell …