An update on best practice of deep brain stimulation in Parkinson's disease

CJ Hartmann, S Fliegen, SJ Groiss… - Therapeutic …, 2019 - journals.sagepub.com
During the last 30 years, deep brain stimulation (DBS) has evolved into the clinical standard
of care as a highly effective treatment for advanced Parkinson's disease. Careful patient …

Precision electronic medicine in the brain

SR Patel, CM Lieber - Nature biotechnology, 2019 - nature.com
Periodically throughout history developments from adjacent fields of science and technology
reach a tipping point where together they produce unparalleled advances, such as the Allen …

Directional DBS increases side‐effect thresholds—a prospective, double‐blind trial

TA Dembek, P Reker, V Visser‐Vandewalle… - Movement …, 2017 - Wiley Online Library
Objective The objective of this study was to investigate whether directional deep brain
stimulation (DBS) of the subthalamic nucleus in Parkinson's disease (PD) offers increased …

[HTML][HTML] Update on current technologies for deep brain stimulation in Parkinson's disease

M Paff, A Loh, C Sarica, AM Lozano… - Journal of movement …, 2020 - ncbi.nlm.nih.gov
Deep brain stimulation (DBS) is becoming increasingly central in the treatment of patients
with Parkinson's disease and other movement disorders. Recent developments in DBS lead …

Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory approaches for …

V Vedam-Mai, K Deisseroth, J Giordano… - Frontiers in Human …, 2021 - frontiersin.org
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …

DiODe: directional orientation detection of segmented deep brain stimulation leads: a sequential algorithm based on CT imaging

A Hellerbach, TA Dembek, M Hoevels… - Stereotactic and …, 2018 - karger.com
Background: Directional deep brain stimulation (DBS) allows steering the stimulation in an
axial direction which offers greater flexibility in programming. However, accurate anatomical …

Thinking small: Progress on microscale neurostimulation technology

JJ Pancrazio, F Deku, A Ghazavi, AM Stiller… - … : Technology at the …, 2017 - Elsevier
Objectives Neural stimulation is well-accepted as an effective therapy for a wide range of
neurological disorders. While the scale of clinical devices is relatively large, translational …

Evolving applications, technological challenges and future opportunities in neuromodulation: proceedings of the fifth annual deep brain stimulation think tank

A Ramirez-Zamora, JJ Giordano, A Gunduz… - Frontiers in …, 2018 - frontiersin.org
The annual Deep Brain Stimulation (DBS) Think Tank provides a focal opportunity for a
multidisciplinary ensemble of experts in the field of neuromodulation to discuss …

Determining the orientation angle of directional leads for deep brain stimulation using computed tomography and digital x‐ray imaging: A phantom study

A Sitz, M Hoevels, A Hellerbach, A Gierich… - Medical …, 2017 - Wiley Online Library
Purpose Orientating the angle of directional leads for deep brain stimulation (DBS) in an
axial plane introduces a new degree of freedom that is indicated by embedded anisotropic …

Role of soft-tissue heterogeneity in computational models of deep brain stimulation

B Howell, CC McIntyre - Brain stimulation, 2017 - Elsevier
Background Bioelectric field models of deep brain stimulation (DBS) are commonly utilized
in research and industrial applications. However, the wide range of different representations …