HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection
PW Hunt, E Sinclair, B Rodriguez… - The Journal of …, 2014 - academic.oup.com
Background. While inflammation predicts mortality in treated human immunodeficiency virus
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …
HIV-associated neurocognitive disorder
DB Clifford, BM Ances - The Lancet infectious diseases, 2013 - thelancet.com
Neurological involvement in HIV is often associated with cognitive impairment. Although
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …
Immunologic biomarkers, morbidity, and mortality in treated HIV infection
PW Hunt, SA Lee, MJ Siedner - The Journal of infectious …, 2016 - academic.oup.com
Despite marked improvements in the modern treatment era, human immunodeficiency virus
(HIV)–infected individuals, particularly those who initiated antiretroviral therapy (ART) at …
(HIV)–infected individuals, particularly those who initiated antiretroviral therapy (ART) at …
Residual immune dysregulation syndrome in treated HIV infection
MM Lederman, NT Funderburg, RP Sekaly… - Advances in …, 2013 - Elsevier
Antiretroviral therapy has revolutionized the course of HIV infection, improving immune
function and decreasing dramatically the mortality and morbidity due to the opportunistic …
function and decreasing dramatically the mortality and morbidity due to the opportunistic …
Systemic inflammation and the increased risk of inflamm-aging and age-associated diseases in people living with HIV on long term suppressive antiretroviral therapy
H Babu, AT Ambikan, EE Gabriel… - Frontiers in …, 2019 - frontiersin.org
The ART program in low-and middle-income countries (LMIC) like India, follows a public
health approach with a standardized regimen for all people living with HIV (PLHIV). Based …
health approach with a standardized regimen for all people living with HIV (PLHIV). Based …
Monocyte/macrophages and their role in HIV neuropathogenesis
Neurological sequelae of human immunodeficiency virus (HIV) infection have been and
remain a significant problem. Monocytes and macrophages in humans and monkeys are …
remain a significant problem. Monocytes and macrophages in humans and monkeys are …
The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure
JH Campbell, AC Hearps, GE Martin, KC Williams… - Aids, 2014 - journals.lww.com
Monocytes and macrophages play critical roles in HIV transmission, viral spread early in
infection, and as a reservoir of virus throughout infection. There has been a recent …
infection, and as a reservoir of virus throughout infection. There has been a recent …
CNS neurotoxicity of antiretrovirals
The development of novel antiretroviral treatments has led to a significant turning point in the
fight against HIV. Although therapy leads to virologic suppression and prolonged life …
fight against HIV. Although therapy leads to virologic suppression and prolonged life …