Covid-19 vaccines—immunity, variants, boosters

DH Barouch - New England Journal of Medicine, 2022 - Mass Medical Soc
Covid-19 Vaccines — Immunity, Variants, Boosters | New England Journal of Medicine Skip to
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The role of inflammation in diabetic retinopathy

JV Forrester, L Kuffova, M Delibegovic - Frontiers in immunology, 2020 - frontiersin.org
Inflammation is central to pathogenic processes in diabetes mellitus and the metabolic
syndrome and particularly implicates innate immunity in the development of complications …

[HTML][HTML] Innate immune evasion by human respiratory RNA viruses

M Kikkert - Journal of innate immunity, 2020 - karger.com
The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2022 - frontiersin.org
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …

Therapeutic targeting of trained immunity

WJM Mulder, J Ochando, LAB Joosten… - Nature reviews Drug …, 2019 - nature.com
Immunotherapy is revolutionizing the treatment of diseases in which dysregulated immune
responses have an important role. However, most of the immunotherapy strategies currently …

Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses

N Grandi, E Tramontano - Frontiers in immunology, 2018 - frontiersin.org
About 8% of our genome is composed of sequences with viral origin, namely human
Endogenous Retroviruses (HERVs). HERVs are relics of ancient infections that affected the …

Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate

RM Lucas, S Yazar, AR Young, M Norval… - Photochemical & …, 2019 - pubs.rsc.org
The Montreal Protocol has limited increases in the UV-B (280–315 nm) radiation reaching
the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the …

The role of PPAR alpha in the modulation of innate immunity

M Grabacka, M Pierzchalska, PM Płonka… - International Journal of …, 2021 - mdpi.com
Peroxisome proliferator-activated receptor α is a potent regulator of systemic and cellular
metabolism and energy homeostasis, but it also suppresses various inflammatory reactions …

Battle royale: innate recognition of poxviruses and viral immune evasion

H Yu, RC Bruneau, G Brennan, S Rothenburg - Biomedicines, 2021 - mdpi.com
Host pattern recognition receptors (PRRs) sense pathogen-associated molecular patterns
(PAMPs), which are molecular signatures shared by different pathogens. Recognition of …