The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Tears have a vital function to protect and lubricate the ocular surface. Tear production,
distribution and clearance is tightly regulated by the lacrimal functional unit (LFU) to meet …

The lipid layer is an essential component of the tear film, providing a smooth optical surface
for the cornea and retarding evaporation from the eye. The meibomian lipids which compose …

In the present update on mucoadhesive ocular dosage forms, the tremendous advances in
the biochemistry of mucins, the development of new polymers, the use of drug complexes …

Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

Publication of the DEWS report in 2007 established the state of the science of dry eye
disease (DED). Since that time, new evidence suggests that a rethinking of traditional …

Tear film stability can be assessed via a number of tools designed for clinical as well as
research purposes. These techniques can give us insights into the tear film, and allow …

The aim of the subcommittee report was to review published evidence describing tear film
changes secondary to contact lens wear and to examine the evidence for associations …

Lubrication is everywhere in the body and essential for the correct operation of biological
systems when subjected to contact stress and wear. The body is like a continuously …