Aldosterone, a vital hormone of the human body, has various pathophysiological roles. The
excess of aldosterone, also known as primary aldosteronism, is the most common …

Aldosterone's role in the kidney and its pathophysiologic actions in hypertension are well
known. However, its role or that of its receptor [minieralocorticoid receptor (MR)] in other …

Background: Adrenaline is believed to play a role in thrombosis and hemostasis. The
complex effect of its clinically relevant concentrations on thrombus formation, coagulation …

Purpose: Steroid hormones in hormonal contraceptives influence a variety of metabolic
parameters. Mainly, ethinyloestradiol (EE) in combined hormonal contraceptives (CHC) is a …

Liver dysfunction manifesting as elevated aminotransferase levels has been a common
feature of coronavirus disease-2019 (COVID-19) infection. The mechanism of liver injury in …

Background While aldosterone plays an important role in blood pressure regulation, its role
in essential hypertension (EHT) remains unclear. Here, we systematically investigated the …

Essential hypertension is a pivotal risk factor for the development of cardiovascular disease
(CVD). Hypertensives exhibit greater stress-induced responses in various physiological …

Platelet endothelial cell adhesion molecule 1 (PECAM-1) is considered an antiplatelet
molecule. Previously, we introduced a new parameter called the PECAM-1/thrombus ratio …

Background The mineralocorticoid hormone aldosterone is a key regulator of the sodium–
potassium balance and blood pressure. In excess, aldosterone relates to hypertension and …

Diabetes is associated with aldosterone excess and the overactivation of its
mineralocorticoid receptor (MR) which leads to the development of many cardiovascular …