[HTML][HTML] snoRNAs: functions and mechanisms in biological processes, and roles in tumor pathophysiology

Z Huang, Y Du, J Wen, B Lu, Y Zhao - Cell Death Discovery, 2022 - nature.com
Small nucleolar RNAs (snoRNAs), a type of non-coding RNA, are widely present in the
nucleoli of eukaryotic cells and play an important role in rRNA modification. With the recent …

Non-coding RNAs: classification, biology and functioning

S Hombach, M Kretz - Non-coding RNAs in colorectal cancer, 2016 - Springer
One of the long-standing principles of molecular biology is that DNA acts as a template for
transcription of messenger RNAs, which serve as blueprints for protein translation. A rapidly …

A census of human RNA-binding proteins

S Gerstberger, M Hafner, T Tuschl - Nature Reviews Genetics, 2014 - nature.com
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …

An updated human snoRNAome

H Jorjani, S Kehr, DJ Jedlinski, R Gumienny… - Nucleic acids …, 2016 - academic.oup.com
Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs that guide the post-
transcriptional processing of other non-coding RNAs (mostly ribosomal RNAs), but have …

mTORC1 signaling controls multiple steps in ribosome biogenesis

V Iadevaia, R Liu, CG Proud - Seminars in cell & developmental biology, 2014 - Elsevier
Ribosome biogenesis is critical for cells to generate the ribosomes they need for protein
synthesis in order to survive, grow and proliferate. It is a complex process, involving the …

[HTML][HTML] Nucleolus and nucleolar stress: from cell fate decision to disease development

L Hua, D Yan, C Wan, B Hu - Cells, 2022 - mdpi.com
Besides the canonical function in ribosome biogenesis, there have been significant recent
advances towards the fascinating roles of the nucleolus in stress response, cell destiny …

[HTML][HTML] Unusual processing generates SPA LncRNAs that sequester multiple RNA binding proteins

H Wu, QF Yin, Z Luo, RW Yao, CC Zheng, J Zhang… - Molecular cell, 2016 - cell.com
We identify a type of polycistronic transcript-derived long noncoding RNAs (lncRNAs) that
are 5′ small nucleolar RNA (snoRNA) capped and 3′ polyadenylated (SPAs). SPA …

Plant-specific features of ribosome biogenesis

BL Weis, J Kovacevic, S Missbach, E Schleiff - Trends in Plant Science, 2015 - cell.com
The biogenesis of eukaryotic ribosomes is a fundamental process involving hundreds of
ribosome biogenesis factors (RBFs) in three compartments of the cell, namely the nucleolus …

A snoRNA modulates mRNA 3′ end processing and regulates the expression of a subset of mRNAs

C Huang, J Shi, Y Guo, W Huang, S Huang… - Nucleic acids …, 2017 - academic.oup.com
Abstract mRNA 3′ end processing is an essential step in gene expression. It is well
established that canonical eukaryotic pre-mRNA 3′ processing is carried out within a …

Non-coding RNAs: Emerging from the discovery to therapeutic applications

B Baptista, M Riscado, JA Queiroz, C Pichon… - Biochemical …, 2021 - Elsevier
The knowledge about non-coding RNAs (ncRNAs) is rapidly increasing with new data
continuously emerging, regarding their diverse types, applications, and roles. Particular …