This is a narrative review on the role of biomarkers in the diagnosis of neonatal sepsis. We
describe the difficulties to obtain standardized definitions in neonatal sepsis and discuss the …

Sepsis is an important cause of mortality and morbidity in neonatal populations. There has
been constant search of an ideal sepsis biomarker that have high sensitivity, specificity …

Neonatal sepsis continues to be a common and significant health care burden, especially in
very-low-birth-weight infants (VLBW< 1500 g). Though intrapartum antibiotic prophylaxis has …

Necrotizing enterocolitis is the leading cause of death due to gastrointestinal disease in
preterm neonates, affecting 5–12% of neonates born at a very-low birth weight. Necrotizing …

Neonatal sepsis is associated with severe morbidity and mortality in the neonatal period.
Clinical manifestations range from subclinical infection to severe local or systemic infection …

Cytokines, including interleukins, interferons, tumor necrosis factors, and chemokines, have
a variety of pro‐and anti‐inflammatory effects in the body through a number of biochemical …

Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Conventional methods utilized for clinical diagnosis of gastrointestinal (GI) diseases have
employed invasive medical procedures that cause stress, anxiety and pain to patients …

Bacterial infections are a major cause of mortality in preterm babies, yet our understanding
of early-life disease-associated immune dysregulation remains limited. Here, we combine …

Twenty percent of very-low-birth-weight (< 1500 g) preterm infants experience a serious
systemic infection, and despite advances in neonatal intensive care and antimicrobials …