Application of molecularly imprinted polymers for electrochemical detection of some important biomedical markers and pathogens

AA Hasseb, OR Shehab, RM El Nashar - Current Opinion in …, 2022 - Elsevier
The determination of biomedical markers and pathogens using electrochemical sensors is a
well-established technique in which the transducer and the recognition element are used to …

Enzyme-based digital bioassay technology–key strategies and future perspectives

H Noji, Y Minagawa, H Ueno - Lab on a Chip, 2022 - pubs.rsc.org
Digital bioassays based on single-molecule enzyme reactions represent a new class of
bioanalytical methods that enable the highly sensitive detection of biomolecules in a …

Computer vision-based artificial intelligence-mediated encoding-decoding for multiplexed microfluidic digital immunoassay

W Zhao, Y Zhou, YZ Feng, X Niu, Y Zhao, J Zhao… - ACS …, 2023 - ACS Publications
Digital immunoassays with multiplexed capacity, ultrahigh sensitivity, and broad affordability
are urgently required in clinical diagnosis, food safety, and environmental monitoring. In this …

A generalizable nanopore sensor for highly specific protein detection at single-molecule precision

M Ahmad, JH Ha, LA Mayse, MF Presti… - Nature …, 2023 - nature.com
Protein detection has wide-ranging implications in molecular diagnostics. Substantial
progress has been made in protein analytics using nanopores and the resistive-pulse …

M13 Bacteriophage-Assisted Recognition and Signal Spatiotemporal Separation Enabling Ultrasensitive Light Scattering Immunoassay

H Fang, Y Zhou, Y Ma, Q Chen, W Tong, S Zhan… - ACS …, 2023 - ACS Publications
The demand for the ultrasensitive and rapid quantitative analysis of trace target analytes has
become increasingly urgent. However, the sensitivity of traditional immunoassay-based …

In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning

M Vasina, D Kovar, J Damborsky, Y Ding, T Yang… - Biotechnology …, 2023 - Elsevier
Nowadays, the vastly increasing demand for novel biotechnological products is supported
by the continuous development of biocatalytic applications that provide sustainable green …

Rationally Designed Functionalization of Single‐Walled Carbon Nanotubes for Real‐Time Monitoring of Cholinesterase Activity and Inhibition in Plasma

S Basu, A Hendler‐Neumark, G Bisker - Small, 2024 - Wiley Online Library
Enzymes play a pivotal role in regulating numerous bodily functions. Thus, there is a
growing need for developing sensors enabling real‐time monitoring of enzymatic activity …

Artificial intelligence-assisted digital immunoassay based on a programmable-particle-decoding technique for multitarget ultrasensitive detection

Y Zhou, W Zhao, Y Feng, X Niu, Y Dong… - Analytical …, 2022 - ACS Publications
The development of a multitarget ultrasensitive immunoassay is significant to fields such as
medical research, clinical diagnosis, and food safety inspection. In this study, an artificial …

Microwell array chip-based single-cell analysis

J Zhang, J Xue, N Luo, F Chen, B Chen, Y Zhao - Lab on a Chip, 2023 - pubs.rsc.org
Single-cell profiling is key to uncover the cellular heterogeneity and drives deep
understanding of cell fate. In recent years, microfluidics has become an ideal tool for single …

A Facile Strategy for Multiplex Protein Detection by a Fluorescent Microsphere-Based Digital Immunoassay

F Gong, Z Tan, X Shan, Y Yang, S Tian… - Analytical …, 2024 - ACS Publications
The digital immunoassay is a highly sensitive detection technique based on single-molecule
counting and is widely used in the ultrasensitive detection of biomarkers. Herein, we …