[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …
[HTML][HTML] Plant flavonoids on oxidative stress-mediated kidney inflammation
S Alsawaf, F Alnuaimi, S Afzal, RM Thomas… - Biology, 2022 - mdpi.com
Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …
Chemopreventive effects of hesperidin against paclitaxel-induced hepatotoxicity and nephrotoxicity via amendment of Nrf2/HO-1 and caspase-3/Bax/Bcl-2 signaling …
Paclitaxel (PTX) is a widely used chemotherapeutic drug particularly effective against lung,
breast, and ovarian cancer, though its usefulness is limited due to its multi-organ toxicity …
breast, and ovarian cancer, though its usefulness is limited due to its multi-organ toxicity …
Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress …
In this study, the potential effects of hesperidin (HES) on chronic toxicity caused by
abamectin (ABM) in the testicular tissue were investigated through oxidative stress …
abamectin (ABM) in the testicular tissue were investigated through oxidative stress …
Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes
Arsenic is widely available in the environment and arsenic toxicity is a public health problem
of serious concern worldwide. Zingerone is a promising phytochemical with various …
of serious concern worldwide. Zingerone is a promising phytochemical with various …
Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …
to cooking or other thermal processes. The aim of present study was to assess the probable …
Hesperidin protects against the chlorpyrifos‐induced chronic hepato‐renal toxicity in rats associated with oxidative stress, inflammation, apoptosis, autophagy, and up …
In this study, we investigated the effects of hesperidin (HSP) on oxidants/antioxidants status,
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
Rutin ameliorates mercuric chloride-induced hepatotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis
Objective Mercury is a global environmental pollutant and is responsible for several organ
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
pathophysiology including oxidative stress-induced liver disorders. Therefore, the present …
The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats
Paclitaxel (PTX), which is widely used in the treatment of solid tumors, leads to dose
limitation because it causes peripheral neuropathy. This study was conducted to evaluate …
limitation because it causes peripheral neuropathy. This study was conducted to evaluate …
Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms
Aim High dose of fluoride intake is associated with toxic effects on liver and kidney tissues.
One approach to tackle these toxicities is using natural antioxidants as supplements. This …
One approach to tackle these toxicities is using natural antioxidants as supplements. This …