The intersection of flow cytometry with microfluidics and microfabrication

ME Piyasena, SW Graves - Lab on a Chip, 2014 - pubs.rsc.org
A modern flow cytometer can analyze and sort particles on a one by one basis at rates of 50
000 particles per second. Flow cytometers can also measure as many as 17 channels of …

Suspension array technology: evolution of the flat-array paradigm

JP Nolan, LA Sklar - TRENDS in Biotechnology, 2002 - cell.com
Suspension arrays of microspheres analyzed using flow cytometry offer a new approach to
multiplexed assays for large-scale screening applications. By optically encoding micron …

Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling

PO Krutzik, GP Nolan - Nature methods, 2006 - nature.com
Flow cytometry allows high-content, multiparameter analysis of single cells, making it a
promising tool for drug discovery and profiling of intracellular signaling. To add high …

Flow cytometry for high-throughput, high-content screening

BS Edwards, T Oprea, ER Prossnitz, LA Sklar - Current opinion in chemical …, 2004 - Elsevier
Flow cytometry is a mature platform for quantitative multi-parameter measurement of cell
fluorescence. Recent innovations allow up to 30-fold faster serial processing of bulk cell …

Multiplex Cellular Assays Using Detectable Cell Barcodes

PO Krutzik, G Nolan - US Patent App. 13/175,566, 2011 - Google Patents
We describe herein a cell-based multiplexing technique called detectable cell barcoding
(DCB). In DCB, each indi vidual sample is labeled with a different DCB signature that …

Multiplex cellular assays using detectable cell barcodes

PO Krutzik, G Nolan - US Patent 8,003,312, 2011 - Google Patents
We describe herein a cell-based multiplexing technique called detectable cell barcoding
(DCB). In DCB, each individual sample is labeled with a different DCB signature that …

[HTML][HTML] A potent and selective inhibitor of Cdc42 GTPase

Z Surviladze, A Waller, JJ Strouse… - Probe Reports from …, 2010 - ncbi.nlm.nih.gov
Cdc42, a member of the Rho family of GTPases, has been shown to play a role in cell
adhesion, cytoskeletal arrangement, phagocytosis and cell motility and migration, in addition …

A cell counting/sorting system incorporated with a microfabricated flow cytometer chip

SY Yang, SK Hsiung, YC Hung… - Measurement …, 2006 - iopscience.iop.org
Flow cytometry is a popular technique for counting and sorting individual cells. This study
presents and demonstrates a new cell counting/sorting system integrated with several …

The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole …

AR Holmes, MV Keniya, I Ivnitski-Steele… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Resistance to the commonly used azole antifungal fluconazole (FLC) can develop due to
overexpression of ATP-binding cassette (ABC) and major facilitator superfamily (MFS) …

Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily …

I Ivnitski-Steele, AR Holmes, E Lamping, BC Monk… - Analytical …, 2009 - Elsevier
Clinically relevant azole resistance in the fungal pathogen Candida albicans is most often
associated with the increased expression of plasma membrane efflux pumps, specifically the …