Importance Opioids are frequently prescribed to children and adolescents after surgery.
Prescription opioid misuse is associated with high-risk behavior in youth. Evidence-based …

A socially patterned epidemic of deaths of despair is a signal feature of American society in
the twenty-first century, involving rising mortality from substance use disorders and self-harm …

GUIDELINES ON THE MANAGEMENT OF CHRONIC PAIN IN CHILDREN v team were
responsible for the systematic reviews. Dr Emma Fisher led the review of effectiveness and …

While US opioid prescribing has decreased 38% in the past decade, opioid deaths have
increased 300%. This opioid paradox is poorly recognized. Current approaches to opioid …

Objective To assess the association between long term prescription opioid treatment
medically dispensed for non-cancer pain and the initiation of injection drug use (IDU) among …

Importance Family members are cited as a common source of prescription opioids used for
nonmedical reasons. However, the overdose risk associated with exposure to opioids …

We describe the historical use of opioids and the scope of the current opioid crisis, review
the differences between dependence and addiction, and the private and public sectors …

Importance Although prescription opioids are the most common way adolescents and young
adults initiate opioid use, many studies examine population-level risks following the first …

This is the first clinical practice guideline (CPG) from the American Academy of Pediatrics
outlining evidence-based approaches to safely prescribing opioids for acute pain in …

Background A wide range of novel psychoactive substances (NPSs) are regularly searched
and discussed online by e-psychonauts. Among NPSs, the range of prescription/non …