A roadmap for metagenomic enzyme discovery
SL Robinson, J Piel, S Sunagawa - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to 2021 Metagenomics has yielded massive amounts of sequencing data
offering a glimpse into the biosynthetic potential of the uncultivated microbial majority. While …
offering a glimpse into the biosynthetic potential of the uncultivated microbial majority. While …
Microbial production of limonene and its derivatives: Achievements and perspectives
Y Ren, S Liu, G Jin, X Yang, YJ Zhou - Biotechnology Advances, 2020 - Elsevier
Limonene and its derivatives have great market potential with diverse applications in food,
pharmaceuticals, cosmetics, etc. Commercial production of limonene and its derivatives …
pharmaceuticals, cosmetics, etc. Commercial production of limonene and its derivatives …
Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria
Carbon-negative synthesis of biochemical products has the potential to mitigate global CO2
emissions. An attractive route to do this is the reverse β-oxidation (r-BOX) pathway coupled …
emissions. An attractive route to do this is the reverse β-oxidation (r-BOX) pathway coupled …
In vitro prototyping of limonene biosynthesis using cell-free protein synthesis
Metabolic engineering of microorganisms to produce sustainable chemicals has emerged
as an important part of the global bioeconomy. Unfortunately, efforts to design and engineer …
as an important part of the global bioeconomy. Unfortunately, efforts to design and engineer …
Acoustic ejection mass spectrometry for high-throughput analysis
We describe a mass spectrometry (MS) analytical platform resulting from the novel
integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and …
integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and …
Total in vitro biosynthesis of the nonribosomal macrolactone peptide valinomycin
Natural products are important because of their significant pharmaceutical properties such
as antiviral, antimicrobial, and anticancer activity. Recent breakthroughs in DNA sequencing …
as antiviral, antimicrobial, and anticancer activity. Recent breakthroughs in DNA sequencing …
Enabling pathway design by multiplex experimentation and machine learning
AG Boob, J Chen, H Zhao - Metabolic Engineering, 2024 - Elsevier
The remarkable metabolic diversity observed in nature has provided a foundation for
sustainable production of a wide array of valuable molecules. However, transferring the …
sustainable production of a wide array of valuable molecules. However, transferring the …
Cell-free styrene biosynthesis at high titers
Styrene is an important petroleum-derived molecule that is polymerized to make versatile
plastics, including disposable silverware and foamed packaging materials. Finding more …
plastics, including disposable silverware and foamed packaging materials. Finding more …
Biological materials: the next frontier for cell-free synthetic biology
Advancements in cell-free synthetic biology are enabling innovations in sustainable
biomanufacturing, that may ultimately shift the global manufacturing paradigm toward …
biomanufacturing, that may ultimately shift the global manufacturing paradigm toward …
Acoustic ejection mass spectrometry: fundamentals and applications in high-throughput drug discovery
C Liu - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Acoustic ejection mass spectrometry (AEMS) is an electrospray ionization-mass
spectrometry (ESI-MS) based analytical platform that provides high analytical throughput …
spectrometry (ESI-MS) based analytical platform that provides high analytical throughput …