Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Diet-induced metabolic endotoxemia is an important factor in the development of many
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …

While mesenchymal stem cells (MSCs)-based therapy appears to be promising, there are
concerns regarding possible side effects related to the unwanted suppression of …

Bacterial sepsis is a major cause of fatality worldwide. Sepsis is a multi-step process that
involves an uncontrolled inflammatory response by the host cells that may result in multi …

Plant antimicrobial peptides (AMPs) are a component of barrier defense system of plants.
They have been isolated from roots, seeds, flowers, stems, and leaves of a wide variety of …

The increasing resistance of pathogen fungi poses a global public concern. There are
several limitations in current antifungals, including few available fungicides, severe toxicity …

Throughout embryonic and early postnatal development, the mammalian epididymis
changes from a straight tube to a highly coiled, complex duct that links the efferent ducts to …

Objectives: To compare changes in vitamin D status and cathelicidin (LL-37) levels in septic
ICU patients treated with placebo versus cholecalciferol. Design: Randomized, placebo …

Selective pressure imposed by millions of years of relentless biological attack has led to the
development of an extraordinary array of defense strategies in plants. Among these …

Vitamin D is an important immune modulator that is linked to infection susceptibility. It has
been suggested that vitamin D deficiency plays a role in sepsis and septic shock because …