Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and
immune defenses, thus resulting in the establishment of infection. The best-characterized …

The role of protein phosphatases in pathogenic bacteria has been studied extensively over
the last two decades. Ser/Thr and Tyr phosphatases are associated with growth and …

Carbon nanotubes are a man-made form of carbon that did not exist in our environment until
very recently. Due to their unique chemical, physical, optical, and magnetic properties …

A total of six nanotherapeutic formulations are already approved for medical use and more
are in the approval pipeline currently. Despite the massive research effort in …

Background. A striking feature of Zaire Ebola virus (ZEBOV) infection in nonhuman primates
is the rapid depletion of T and NK lymphocytes by apoptosis. In a mouse model of ZEBOV …

The mammalian immune system comprises multiple physical, chemical, and cellular
components that are traditionally classified as innate and adaptive immunity. The innate …

Human-pathogenic Yersinia produce plasmid-encoded Yersinia outer proteins (Yops),
which are necessary to down-regulate anti-bacterial responses that constrict bacterial …

Pathogenic species of the genus Yersinia suppress and reorient the immune system to infect
lymphatic tissues, inner organs and at times also the vasculature. For this purpose yersiniae …

The protein tyrosine phosphatase PEST (PTP-PEST) is involved in the regulation of the actin
cytoskeleton. Despite the emerging functions attributed to both PTPs and the actin …

Staphylococcus aureus is a dangerous pathogen that evolved refined immuno-evasive
strategies to antagonize host immune responses. This involves the biogenesis of death …