Deuterium metabolic imaging (DMI) is an emerging clinically-applicable technique for the
non-invasive investigation of tissue metabolism. The generally short T 1 values of 2 H …

Hyperpolarized carbon 13 MRI (13C MRI) is a novel imaging approach that can
noninvasively probe tissue metabolism in both normal and pathologic tissues. The process …

Abstract MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can
measure processes such as localized metabolism that is altered in numerous cancers, liver …

Tumour metabolism can be imaged with a novel imaging technique termed hyperpolarised
carbon-13 (13 C)-MRI using probes, ie, endogenously found molecules that are labeled with …

Hyperpolarization techniques increase nuclear spin polarization by more than four orders of
magnitude, enabling metabolic MRI. Even though hyperpolarization has shown clear value …

Hyperpolarization techniques significantly enhance the sensitivity of magnetic resonance
(MR) and thus present fascinating new directions for research and applications with in vivo …

One of the hallmarks of cancer is metabolic reprogramming, including high levels of aerobic
glycolysis (the Warburg effect). Pyruvate is a product of glucose metabolism, and 13C-MR …

Given growing clinical needs, in recent years Artificial Intelligence (AI) techniques have
increasingly been used to define the best approaches for survival assessment and …

Abstract Background Dynamic hyperpolarized (HP)-13 C MRI has enabled real-time, non-
invasive assessment of Warburg-related metabolic dysregulation in glioma using a [1-13 C] …

Simple Summary Glioma is the most common primary brain tumour and main cause of death
of those with primary brain tumours. Multiple studies have demonstrated that glioma patients …