[PDF][PDF] Recent Advances in Our Understanding of Age-Related Macular Degeneration: Mitochondrial Dysfunction, Redox Signaling, and the Complement System

F Buonfiglio, CA Korb, B Stoffelns, N Pfeiffer… - Aging Dis., 2024 - researchgate.net
Age-related macular degeneration (AMD) is a prevalent degenerative disorder of the central
retina, which holds global significance as the fourth leading cause of blindness. The …

[HTML][HTML] High-density optical coherence tomography analysis provides insights into early/intermediate age-related macular degeneration retinal layer changes

M Trinh, M Kalloniatis, D Alonso-Caneiro… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: To topographically map all of the thickness differences in individual retinal layers
between early/intermediate age-related macular degeneration (AMD early/AMD int) and …

Modelling normal age-related changes in individual retinal layers using location-specific OCT analysis

M Trinh, V Khou, B Zangerl, M Kalloniatis… - Scientific Reports, 2021 - nature.com
Current descriptions of retinal thickness across normal age cohorts are mostly limited to
global analyses, thus overlooking spatial variation across the retina and limiting spatial …

[HTML][HTML] Spatial cluster patterns of retinal sensitivity loss in intermediate age-related macular degeneration features

M Trinh, M Kalloniatis… - … Vision Science & …, 2023 - iovs.arvojournals.org
Purpose: To examine spatial patterns of retinal sensitivity loss in the three key features of
intermediate age-related macular degeneration (iAMD). Methods: One-hundred individuals …

[HTML][HTML] Reticular pseudodrusen are associated with more advanced para-central photoreceptor degeneration in intermediate age-related macular degeneration

M Trinh, N Eshow, D Alonso-Caneiro… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: The purpose of this study was to examine retinal topographical differences
between intermediate age-related macular degeneration (iAMD) with reticular …

Age related grid-wise spatial analysis of choroidal parameters in well characterised healthy population

M Kumar, M Trinh, A Zhang, X Wei, R Agrawal… - Scientific Reports, 2024 - nature.com
Choroidal vascularity index (CVI) is an image-based metric applied to assess the choroid in
disease but poorly explored in natural aging. In this retrospective cohort study, we assessed …

Location-specific thickness patterns in intermediate age-related macular degeneration reveals anatomical differences in multiple retinal layers

M Trinh, V Khou, M Kalloniatis… - … & Visual Science, 2021 - iovs.arvojournals.org
Purpose: To examine individual retinal layers' location-specific patterns of thicknesses in
intermediate age-related macular degeneration (iAMD) using optical coherence tomography …

Inner retinal layer thickness alterations in early age related macular degeneration in eyes with subretinal drusenoid deposits or conventional Drusen

S Abdolrahimzadeh, M Di Pippo, E Sordi… - Journal of clinical …, 2021 - mdpi.com
The purpose of this study was to evaluate central and parafoveal inner retinal layer
thickness in patients with subretinal drusenoid deposits (SDD) or conventional drusen (CD) …

Should clinical automated perimetry be considered for routine functional assessment of early/intermediate age‐related macular degeneration (AMD)? A systematic …

M Trinh, M Kalloniatis… - … and Physiological Optics, 2022 - Wiley Online Library
Purpose There is growing interest in functional testing for early/intermediate age‐related
macular degeneration (iAMD). However, systematic evaluation of existing clinical functional …

Derivation of human retinal cell densities using high‐density, spatially localized optical coherence tomography data from the human retina

J Tong, V Khou, M Trinh… - Journal of …, 2023 - Wiley Online Library
This study sought to identify demographic variations in retinal thickness measurements from
optical coherence tomography (OCT), to enable the calculation of cell density parameters …