Bacterial strain typing, or identifying bacteria at the strain level, is particularly important for
diagnosis, treatment, and epidemiological surveillance of bacterial infections. This is …

Glanders or farcy, caused by Burkholderia mallei, is an infectious and zoonotic disease of
solipeds. Horses, donkeys and mules are the only known natural reservoir of B. mallei …

Abstract The Xylariaceae (Sordariomycetes) comprise one of the largest and most diverse
families of Ascomycota, with at least 85 accepted genera and ca. 1343 accepted species. In …

Background Diverse bacterial genomes encode numerous small non-coding RNAs (sRNAs)
that regulate myriad biological processes. While bioinformatic algorithms have proven …

Background Phylogeographic reconstruction of some bacterial populations is hindered by
low diversity coupled with high levels of lateral gene transfer. A comparison of …

Burkholderia pseudomallei, the etiologic agent of human melioidosis, is capable of causing
severe acute infection with overwhelming septicemia leading to death. A high rate of …

Burkholderia pseudomallei is a Gram-negative bacterium that causes the serious human
disease, melioidosis. There is no vaccine against melioidosis and it can be fatal if not treated …

Glanders is the contagious zoonotic disease caused by infection with Burkholderia mallei. It
affects primarily horses, donkeys and mules. The disease was eradicated from large areas …

Burkholderia mallei is the etiological agent of glanders, a highly contagious and often fatal
disease in equids. Due to the high genetic clonality of B. mallei, high-resolution typing …

Unwanted evolution can rapidly degrade the performance of genetically engineered circuits
and metabolic pathways installed in living organisms. We created the Evolutionary Failure …