A perspective on the prospective use of AI in protein structure prediction
R Versini, S Sritharan, B Aykac Fas… - Journal of Chemical …, 2023 - ACS Publications
AlphaFold2 (AF2) and RoseTTaFold (RF) have revolutionized structural biology, serving as
highly reliable and effective methods for predicting protein structures. This article explores …
highly reliable and effective methods for predicting protein structures. This article explores …
Interplay between RNA viruses and cGAS/STING axis in innate immunity
While the function of cGAS/STING signalling axis in the innate immune response to DNA
viruses is well deciphered, increasing evidence demonstrates its significant contribution in …
viruses is well deciphered, increasing evidence demonstrates its significant contribution in …
Molecular architecture of the Chikungunya virus replication complex
To better understand how positive-strand (+) RNA viruses assemble membrane-associated
replication complexes (RCs) to synthesize, process, and transport viral RNA in virus-infected …
replication complexes (RCs) to synthesize, process, and transport viral RNA in virus-infected …
Architecture of the chikungunya virus replication organelle
T Laurent, P Kumar, S Liese, F Zare, M Jonasson… - Elife, 2022 - elifesciences.org
Alphaviruses are mosquito-borne viruses that cause serious disease in humans and other
mammals. Along with its mosquito vector, the Alphavirus chikungunya virus (CHIKV) has …
mammals. Along with its mosquito vector, the Alphavirus chikungunya virus (CHIKV) has …
Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores
Alphaviruses are emerging positive-stranded RNA viruses which replicate and transcribe
their genomes in membranous organelles formed in the cell cytoplasm. The nonstructural …
their genomes in membranous organelles formed in the cell cytoplasm. The nonstructural …
Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold
Abstract Alphaviruses such as Ross River virus (RRV), chikungunya virus (CHIKV), Sindbis
virus (SINV), and Venezuelan equine encephalitis virus (VEEV) are mosquito-borne …
virus (SINV), and Venezuelan equine encephalitis virus (VEEV) are mosquito-borne …
Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching
H Zhan, N Unchwaniwala… - Proceedings of the …, 2023 - National Acad Sciences
Positive-strand RNA viruses replicate their genomes in virus-induced membrane vesicles,
and the resulting RNA replication complexes are a major target for virus control. Nodavirus …
and the resulting RNA replication complexes are a major target for virus control. Nodavirus …
Alphavirus RNA replication in vertebrate cells
T Ahola, G McInerney, A Merits - Advances in virus research, 2021 - Elsevier
Alphaviruses are positive-strand RNA viruses, typically transmitted by mosquitoes between
vertebrate hosts. They encode four essential replication proteins, the non-structural proteins …
vertebrate hosts. They encode four essential replication proteins, the non-structural proteins …
Crowning touches in positive-strand RNA virus genome replication complex structure and function
M Nishikiori, JA den Boon… - Annual Review of …, 2022 - annualreviews.org
Positive-strand RNA viruses, the largest genetic class of eukaryotic viruses, include
coronaviruses and many other established and emerging pathogens. A major target for …
coronaviruses and many other established and emerging pathogens. A major target for …
De novo modelling of HEV replication polyprotein: Five-domain breakdown and involvement of flexibility in functional regulation
S Fieulaine, T Tubiana, S Bressanelli - Virology, 2023 - Elsevier
Hepatitis E virus (HEV), a major cause of acute viral hepatitis, is a single-stranded, positive-
sense RNA virus. As such, it encodes a 1700-residue replication polyprotein pORF1 that …
sense RNA virus. As such, it encodes a 1700-residue replication polyprotein pORF1 that …