Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens
J Gao, H Hou, F Gao - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …
The antibacterial activity of fluoroquinolone derivatives: An update (2018–2021)
Y Jia, L Zhao - European journal of medicinal chemistry, 2021 - Elsevier
Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …
[HTML][HTML] In vitro antimicrobial evaluation, single-point resistance study, and radiosterilization of novel pyrazole incorporating thiazol-4-one/thiophene derivatives as …
HA Mohamed, YA Ammar, GAM Elhagali, HA Eyada… - ACS …, 2022 - ncbi.nlm.nih.gov
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
Synthesis, characterization, DFT, biological activity evaluation, and molecular docking analysis of new 8-[(2-hydroxynaphthalen-1-yl) diazenyl] naphthalene-1, 3 …
Three novel metal complexes of 2‑hydroxy-1-naphthaldehyde azine (HNANSA) with iron
(III), nickel (II), and copper (II) have been synthesized and characterized. Various analytical …
(III), nickel (II), and copper (II) have been synthesized and characterized. Various analytical …
A comprehensive review of recent advances in the biological activities of 1, 2, 4‐oxadiazoles
OM Hendawy - Archiv der Pharmazie, 2022 - Wiley Online Library
Nitrogen heterocycles play an essential role in medication development. The 1, 2, 4‐
oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules …
oxadiazole heterocycle has been extensively studied, yielding a large variety of molecules …
In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual …
H Ali Mohamed, YA Ammar, G AM Elhagali… - ACS …, 2022 - ACS Publications
A series of thiazol-4-one/thiophene-bearing pyrazole derivatives as pharmacologically
attractive cores were initially synthesized using a hybridization approach. All structures were …
attractive cores were initially synthesized using a hybridization approach. All structures were …
Synthesis, X-ray crystallography and antimicrobial activity of 2-cyanoguanidinophenytoin
The optimized synthesis of [5-oxo-4, 4-diphenylimidazolidin-2-ylidene] cyanamide, which is
known as 2-cyanoguanidinophenytoin (CNG-DPH)(3), and (imidazo [4, 5-d] imidazole-2, 5 …
known as 2-cyanoguanidinophenytoin (CNG-DPH)(3), and (imidazo [4, 5-d] imidazole-2, 5 …
Cupressus sempervirens Essential Oil: Exploring the Antibacterial Multitarget Mechanisms, Chemcomputational Toxicity Prediction, and Safety Assessment in …
S Akermi, S Smaoui, K Elhadef, M Fourati, N Louhichi… - Molecules, 2022 - mdpi.com
Nowadays, increasing interest has recently been given to the exploration of new food
preservatives to avoid foodborne outbreaks or food spoilage. Likewise, new compounds that …
preservatives to avoid foodborne outbreaks or food spoilage. Likewise, new compounds that …
Design and Synthesis of 2-(4-Bromophenyl)Quinoline-4-Carbohydrazide Derivatives via Molecular Hybridization as Novel Microbial DNA-Gyrase Inhibitors
Microbial DNA gyrase is regarded as an outstanding microbial target. Hence, 15 new
quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of …
quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of …
[HTML][HTML] Novel 1, 2, 4-oxadiazole/pyrrolidine hybrids as DNA gyrase and topoisomerase IV inhibitors with potential antibacterial activity
FOA Frejat, Y Cao, H Zhai, SA Abdel-Aziz… - Arabian Journal of …, 2022 - Elsevier
DNA gyrase is a promising target for antibacterial agents. Several classes of small-molecule
inhibitors have been discovered in recent decades, but none of these have reached the …
inhibitors have been discovered in recent decades, but none of these have reached the …