Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …

Background Within the last few years, it has become evident that LPS-preconditioned
mesenchymal stromal cells (LPS pre-MSCs) show enhanced paracrine effects, including …

Exosomes are served as substitutes for stem cell therapy, playing important roles in
mediating heart repair during myocardial infarction injury. Evidence have indicated that …

The lack of therapies for progressive multiple sclerosis highlights the need to understand the
regenerative process of remyelination that can follow CNS demyelination. This involves an …

Research into mesenchymal stromal/stem cells (MSCs) has been particularly exciting in the
past five years. Our understanding of mechanisms of MSC-mediated tissue regeneration has …

Despite improvements in interventional and pharmacological therapy of atherosclerotic
disease, it is still the leading cause of death in the developed world. Hence, there is a need …

In the past decade, substantial evidence supports the paradigm that stem cells exert their
reparative and regenerative effects, in large part, through the release of biologically active …

Abstract Background Mesenchymal stem cells (MSCs) have a therapeutic potential in tissue
repair because of capacity for multipotent differentiation and their ability to modulate the …

Tendon healing follows a complex series of coordinated events, which ultimately produces a
mechanically inferior tissue more scar-like than native tendon. More regenerative healing …