Promises and pitfalls of untargeted metabolomics

I Gertsman, BA Barshop - Journal of inherited metabolic disease, 2018 - Springer
Metabolomics is one of the newer omics fields, and has enabled researchers to complement
genomic and protein level analysis of disease with both semi-quantitative and quantitative …

Evaluating and minimizing batch effects in metabolomics

W Han, L Li - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Determining metabolomic differences among samples of different phenotypes is a critical
component of metabolomics research. With the rapid advances in analytical tools such as …

Dietary fructose alters the composition, localization, and metabolism of gut microbiota in association with worsening colitis

DC Montrose, R Nishiguchi, S Basu, HA Staab… - Cellular and molecular …, 2021 - Elsevier
Background & Aims The incidence of inflammatory bowel diseases has increased over the
last half century, suggesting a role for dietary factors. Fructose consumption has increased in …

Addressing the batch effect issue for LC/MS metabolomics data in data preprocessing

Q Liu, D Walker, K Uppal, Z Liu, C Ma, VL Tran, S Li… - Scientific reports, 2020 - nature.com
With the growth of metabolomics research, more and more studies are conducted on large
numbers of samples. Due to technical limitations of the Liquid Chromatography–Mass …

Quantitative challenges and their bioinformatic solutions in mass spectrometry-based metabolomics

H Yu, B Low, Z Zhang, J Guo, T Huan - TrAC Trends in Analytical …, 2023 - Elsevier
Improving the quantitative performance of mass spectrometry (MS)-based metabolomics is
the key to its successful application in a broad range of research questions. Like other …

Standardization procedures for real-time breath analysis by secondary electrospray ionization high-resolution mass spectrometry

KD Singh, G Tancev, F Decrue, J Usemann… - Analytical and …, 2019 - Springer
Despite the attractiveness of breath analysis as a non-invasive means to retrieve relevant
metabolic information, its introduction into routine clinical practice remains a challenge …

Quantifying Cell Heterogeneity and Subpopulations Using Single Cell Metabolomics

R Liu, J Li, Y Lan, TD Nguyen, YA Chen… - Analytical …, 2023 - ACS Publications
Mass spectrometry (MS) has become an indispensable tool for metabolomics studies.
However, due to the lack of applicable experimental platforms, suitable algorithm, software …

Tools and resources for metabolomics research community: A 2017–2018 update

BB Misra, S Mohapatra - Electrophoresis, 2019 - Wiley Online Library
The scale at which MS‐and NMR‐based platforms generate metabolomics datasets for both
research, core, and clinical facilities to address challenges in the various sciences—ranging …

Mass spectrometric identification of urinary biomarkers of pulmonary tuberculosis

F Isa, S Collins, MH Lee, D Decome, N Dorvil… - …, 2018 - thelancet.com
Background Tuberculosis (TB) is the leading infectious cause of death worldwide. A major
barrier to control of the pandemic is a lack of clinical biomarkers with the ability to distinguish …

Personalized nutrition: translating the science of nutrigenomics into practice: proceedings from the 2018 American College of Nutrition Meeting

OI Aruoma, S Hausman-Cohen, J Pizano… - Journal of the …, 2019 - Taylor & Francis
Adverse reactions to foods and adverse drug reactions are inherent in product defects,
medication errors, and differences in individual drug exposure. Pharmacogenetics is the …