Probiotics are frequently consumed as functional food and widely used as dietary
supplements, but are also recommended in treating or preventing various gastrointestinal …

The human gut microbiome is a complex microbial community that is strongly linked to both
host health and disease. However, the detailed molecular mechanisms underlying the …

As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …

Relationship between drugs and microbiota is bilateral. Proper composition thus function of
microbiota is a key to some medications used in modern medicine. However, there is also …

Introduction The trillions of microorganisms that comprise the gut microbiome form dynamic
bidirectional interactions with orally administered drugs and host health. These relationships …

Metabolomics by gas chromatography/mass spectrometry (GC/MS) provides a standardized
and reliable platform for understanding small molecule biology. Since 2005, the West Coast …

Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and the leading
cause of cancer-associated deaths. Epidemiological studies have shown that both genetic …

Oleandrin is a highly lipid-soluble cardiac glycoside isolated from the plant Nerium oleander
(Apocynaceae) and is used as a traditional herbal medicine due to its excellent …

Metabolomics samples like human urine or serum contain upwards of a few thousand
metabolites, but individual analytical techniques can only characterize a few hundred …

Food ingestion affects the oral absorption of many drugs in humans. In this review article, we
summarize the physiological factors in the gastrointestinal (GI) tract that affect the in vivo …