The goldmine of GWAS summary statistics: a systematic review of methods and tools

PI Kontou, PG Bagos - BioData Mining, 2024 - Springer
Genome-wide association studies (GWAS) have revolutionized our understanding of the
genetic architecture of complex traits and diseases. GWAS summary statistics have become …

Gradualism, natural selection, and the randomness of mutation–fisher, Kimura, and Orr, connecting the dots

MJ Maxwell, E Sober - Biology & Philosophy, 2023 - Springer
Evolutionary gradualism, the randomness of mutations, and the hypothesis that natural
selection exerts a pervasive and substantial influence on evolutionary outcomes are pair …

Leveraging the microbiome in host genome wide association studies

D Awany - 2021 - open.uct.ac.za
Genome-wide association study (GWAS) has emerged as an effective method for detecting
genetic polymorphisms associated with expressed phenotypes. Over the past decade …

BEND4 as a Candidate Gene for an Infection-Induced Acute Encephalopathy Characterized by a Cyst and Calcification of the Pons and Cerebellar Atrophy

B Kara, O Uyguner, H Maraş Genç, EE İşlek… - Molecular …, 2022 - karger.com
Three siblings born to Turkish parents from the same village had normal brain development
until acute neurological deterioration between 12 months and 8 years of age. Consequent …