Lipid nanoparticle-mediated drug delivery to the brain

P Khare, SX Edgecomb, CM Hamadani… - Advanced Drug Delivery …, 2023 - Elsevier
Lipid nanoparticles (LNPs) have revolutionized the field of drug delivery through their
applications in siRNA delivery to the liver (Onpattro) and their use in the Pfizer-BioNTech …

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems

CH Villa, AC Anselmo, S Mitragotri… - Advanced drug delivery …, 2016 - Elsevier
Red blood cells (RBCs) constitute a unique drug delivery system as a biologic or hybrid
carrier capable of greatly enhancing pharmacokinetics, altering pharmacodynamics (for …

Anatomy of the red cell membrane skeleton: unanswered questions

SE Lux IV - Blood, The Journal of the American Society of …, 2016 - ashpublications.org
The red cell membrane skeleton is a pseudohexagonal meshwork of spectrin, actin, protein
4.1 R, ankyrin, and actin-associated proteins that laminates the inner membrane surface and …

The SLC4 family of bicarbonate (HCO3-) transporters

MF Romero, AP Chen, MD Parker, WF Boron - Molecular aspects of …, 2013 - Elsevier
The SLC4 family consists of 10 genes (SLC4A1–5; SLC4A7–11). All encode integral
membrane proteins with very similar hydropathy plots—consistent with 10–14 …

Even patients with mild COVID‐19 symptoms after SARS‐CoV‐2 infection show prolonged altered red blood cell morphology and rheological parameters

M Grau, L Ibershoff, J Zacher, J Bros… - Journal of cellular …, 2022 - Wiley Online Library
Infection with the novel severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)
and the associated coronavirus disease‐19 (COVID‐19) might affect red blood cells (RBC); …

Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders

SE Iismaa, BM Mearns, L Lorand… - Physiological …, 2009 - journals.physiology.org
The human transglutaminase (TG) family consists of a structural protein, protein 4.2, that
lacks catalytic activity, and eight zymogens/enzymes, designated factor XIII-A (FXIII-A) and …

[HTML][HTML] Plasma membrane lipid domains as platforms for vesicle biogenesis and shedding?

H Pollet, L Conrard, AS Cloos, D Tyteca - Biomolecules, 2018 - mdpi.com
Extracellular vesicles (EVs) contribute to several pathophysiological processes and appear
as emerging targets for disease diagnosis and therapy. However, successful translation from …

[图书][B] The structure of biological membranes

PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice

TH Lee, SU Kim, SL Yu, SH Kim, DS Park, HB Moon… - Blood, 2003 - ashpublications.org
Peroxiredoxins (Prxs) are a family of antioxidant proteins that reduce peroxide levels by
using reducing agents such as thioredoxin. These proteins were characterized to have a …

A band 3–based macrocomplex of integral and peripheral proteins in the RBC membrane

LJ Bruce, R Beckmann, ML Ribeiro… - Blood, The Journal …, 2003 - ashpublications.org
We have studied the membrane proteins of band 3 anion exchanger (AE1)–deficient mouse
and human red blood cells. It has been shown previously that proteins of the band 3 …