While Nature harnesses RNA and DNA to store, read and write genetic information, the
inherent programmability, synthetic accessibility and wide functionality of these nucleic acids …

Labeling of nucleic acids is required for many studies aiming to elucidate their functions and
dynamics in vitro and in cells. Out of the numerous labeling concepts that have been …

The COVID-19 pandemic has elevated mRNA vaccines to global recognition due to their
unprecedented success rate in protecting against a deadly virus. This international success …

Germ granules, condensates of phase-separated RNA and protein, are organelles that are
essential for germline development in different organisms. The patterning of the granules …

The mRNA modification N6‐methyladenosine (m6A) is associated with multiple roles in cell
function and disease. The methyltransferases METTL3‐METTL14 and METTL16 act as …

Eukaryotic mRNAs are emerging modalities for protein replacement therapy and
vaccination. Their 5′ cap is important for mRNA translation and immune response and can …

Conspectus The central dogma of molecular biology hinges on messenger RNA (mRNA),
which presents a blueprint of the genetic information encoded in the DNA and serves as a …

To understand the structure and ensuing function of RNA in various cellular processes,
researchers greatly rely on traditional as well as contemporary labeling technologies to …

The transition state model of cell differentiation proposes that a transient window of gene
expression stochasticity precedes entry into a differentiated state. Here, we assess this …

RNA is a central molecule in numerous cellular processes, including transcription,
translation, and regulation of gene expression. To reveal the numerous facets of RNA …