Teratogenicity of antiepileptic drugs

T Tomson, D Battino, E Perucca - Current opinion in neurology, 2019 - journals.lww.com
The risk of adverse fetal effects differs in relation to the type of AED and for some AEDs also
the daily dose. Although for MCMs the risk is primarily associated with the first trimester of …

Treatment and care of women with epilepsy before, during, and after pregnancy: a practical guide

B Nucera, F Brigo, E Trinka… - Therapeutic advances in …, 2022 - journals.sagepub.com
Women with epilepsy (WWE) wishing for a child represent a highly relevant subgroup of
epilepsy patients. The treating epileptologist needs to delineate the epilepsy syndrome and …

Comparative safety of antiseizure medication monotherapy for major malformations

JM Cohen, S Alvestad, CE Cesta, MH Bjørk… - Annals of …, 2023 - Wiley Online Library
Objective This study was undertaken to examine the comparative safety of antiseizure
medication (ASM) monotherapy in pregnancy with respect to risk of major congenital …

Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs

PO Blotière, F Raguideau, A Weill, E Elefant, I Perthus… - Neurology, 2019 - AAN Enterprises
Objective To assess the association between exposure to monotherapy with 10 different
antiepileptic drugs (AEDs) during the first 2 months of pregnancy and the risk of 23 major …

Neonatal and maternal adverse outcomes and exposure to nonsteroidal anti-inflammatory drugs during early pregnancy in South Korea: A nationwide cohort study

EY Choi, HE Jeong, Y Noh, A Choi, DK Yon… - PLoS …, 2023 - journals.plos.org
Background Existing data on the use of nonsteroidal anti-inflammatory drugs (NSAIDs)
during late pregnancy is well established, providing assurance. However, the use of NSAIDs …

Characteristics of prescription opioid analgesics in pregnancy and risk of neonatal opioid withdrawal syndrome in newborns

DB Esposito, KF Huybrechts, MM Werler… - JAMA network …, 2022 - jamanetwork.com
Importance Prescription opioids are often used during pregnancy even though they are
associated with neonatal opioid withdrawal syndrome (NOWS). Most studies of adverse …

Prenatal exposure to pregabalin, birth outcomes and neurodevelopment–a population-based cohort study in four Nordic countries

E Dudukina, SK Szépligeti, P Karlsson, K Asomaning… - Drug Safety, 2023 - Springer
Introduction Pregabalin is an antiepileptic drug frequently prescribed to pregnant women.
Risks of adverse birth and postnatal neurodevelopmental outcomes following prenatal …

Relation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth

AV Margulis, S Hernandez-Diaz, T McElrath… - PloS one, 2019 - journals.plos.org
Background The associations of individual antiepileptic drugs (AEDs) with pregnancy
duration and size at birth, and potential dose relations, are not well characterized. Methods …

Management of anti-seizure medications during pregnancy: advancements in the past decade

C Avachat, JM Barry, X Lyu, CM Sherwin, AK Birnbaum - Pharmaceutics, 2022 - mdpi.com
Management of seizures often involves continuous medication use throughout a patient's
life, including when a patient is pregnant. The physiological changes during pregnancy can …

[HTML][HTML] Pregnancy-related lumbosacral pain

FF Aragão - BrJP, 2019 - SciELO Brasil
ABSTRACT BACKGROUND AND OBJECTIVES: Pregnancy causes physiological and
anatomical changes in the woman's body, affecting several systems such as the …