Existing guidelines on the preparation (Planning Research and Experimental Procedures on
Animals: Recommendations for Excellence (PREPARE)) and reporting (Animal Research …

Background Predictive preclinical models play an important role in the assessment of new
treatment strategies and as avatar models for personalised medicine; however, reliable and …

Musculoskeletal sarcomas pose major challenges to researchers and clinicians due to their
rarity and heterogeneity. Xenografting human cells or tumor fragments in rodents is a …

Simple Summary Adrenocortical carcinoma (ACC) is a rare, often deadly cancer arising from
the adrenal gland. Mortality associated with ACC has remained unchanged over the last …

Background/Aim: To maximize success rate for development of HER2-targeted therapeutics,
patient-derived xenograft (PDX) models reflecting HER2-positive gastric cancer (HER2+ …

Background Neuroblastoma is a highly lethal malignancy of young children. Mesenchymal
stromal cells (MSCs) may represent a novel cellular delivery vehicle due to their innate …

Background: Neuroblastoma is a common pediatric solid tumor with poor outcomes in high-
risk patients. The identification of new therapeutic biomarkers is critical for the treatment of …

Noninvasive, robust, and reproducible methods to image kidneys are provided by different
imaging modalities. A combination of modalities (multimodality) can give better insight into …

Background/Aim: Neuroblastoma is a common childhood cancer with poor survival for
children with high-risk disease, and ongoing research to improve outcomes is needed …

Ewing sarcoma (EWS) is a bone-and soft tissue tumour affecting primarily children and
young adults. A quarter of patients present with metastases at the time of diagnosis and …