Is oxytocin “nature's medicine”?
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …
Epigenetic modifications in stress response genes associated with childhood trauma
Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
Hormonal treatments for major depressive disorder: state of the art
Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
[HTML][HTML] Stress: endocrine physiology and pathophysiology
C Tsigos, I Kyrou, E Kassi, GP Chrousos - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Stress constitutes a state of threatened homeostasis triggered by intrinsic or extrinsic
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
The oxytocin–vasopressin pathway in the context of love and fear
CS Carter - Frontiers in endocrinology, 2017 - frontiersin.org
Vasopressin (VP) and oxytocin (OT) are distinct molecules; these peptides and their
receptors [OT receptor (OTR) and V1a receptor (V1aR)] also are evolved components of an …
receptors [OT receptor (OTR) and V1a receptor (V1aR)] also are evolved components of an …
The HPA axis as target for depression
A Menke - Current Neuropharmacology, 2024 - benthamdirect.com
Major depressive disorder (MDD) is a stress-related mental disorder with a lifetime
prevalence of 20% and, thus, is one of the most prevalent mental health disorders …
prevalence of 20% and, thus, is one of the most prevalent mental health disorders …
[HTML][HTML] The biology of vasopressin
S Sparapani, C Millet-Boureima, J Oliver, K Mu… - Biomedicines, 2021 - mdpi.com
Vasopressins are evolutionarily conserved peptide hormones. Mammalian vasopressin
functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for …
functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for …
Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition
The characterization of germline genetic variation affecting cancer risk, known as cancer
predisposition, is fundamental to preventive and personalized medicine. Studies of genetic …
predisposition, is fundamental to preventive and personalized medicine. Studies of genetic …
Biomarkers associated with cardiovascular disease in COVID-19
CC Kaufmann, A Ahmed, AL Burger, M Muthspiel… - Cells, 2022 - mdpi.com
Coronavirus disease-19 (COVID-19) emerged late December 2019 in the city of Wuhan,
China and has since spread rapidly all over the world causing a global pandemic. While the …
China and has since spread rapidly all over the world causing a global pandemic. While the …
Long-term health outcomes associated with hydration status
NI Dmitrieva, M Boehm, PH Yancey… - Nature Reviews …, 2024 - nature.com
Body water balance is determined by fundamental homeostatic mechanisms that maintain
stable volume, osmolality and the composition of extracellular and intracellular fluids. Water …
stable volume, osmolality and the composition of extracellular and intracellular fluids. Water …