[HTML][HTML] Invited review: Inbreeding in the genomics era: Inbreeding, inbreeding depression, and management of genomic variability
Traditionally, pedigree-based relationship coefficients have been used to manage the
inbreeding and degree of inbreeding depression that exists within a population. The …
inbreeding and degree of inbreeding depression that exists within a population. The …
[HTML][HTML] Symposium review: The genomic architecture of inbreeding: How homozygosity affects health and performance
Inbreeding depression is a growing concern in livestock because it can detrimentally affect
animal fitness, health, and production levels. Genomic information can be used to more …
animal fitness, health, and production levels. Genomic information can be used to more …
[HTML][HTML] Effect of genomic selection on rate of inbreeding and coancestry and effective population size of Holstein and Jersey cattle populations
Genetic diversity in livestock populations is a significant contributor to the sustainability of
animal production. Also, genetic diversity allows animal production to become more …
animal production. Also, genetic diversity allows animal production to become more …
Structural variant-based pangenome construction has low sensitivity to variability of haplotype-resolved bovine assemblies
Advantages of pangenomes over linear reference assemblies for genome research have
recently been established. However, potential effects of sequence platform and assembly …
recently been established. However, potential effects of sequence platform and assembly …
[HTML][HTML] How genomic selection has increased rates of genetic gain and inbreeding in the Australian national herd, genomic information nucleus, and bulls
Genomic selection has been commonly used for selection for over a decade. In this time, the
rate of genetic gain has more than doubled in some countries, while inbreeding per year has …
rate of genetic gain has more than doubled in some countries, while inbreeding per year has …
Trends in genome-wide and region-specific genetic diversity in the Dutch-Flemish Holstein–Friesian breeding program from 1986 to 2015
Abstract Background In recent decades, Holstein–Friesian (HF) selection schemes have
undergone profound changes, including the introduction of optimal contribution selection …
undergone profound changes, including the introduction of optimal contribution selection …
Genetic diversity in the Italian Holstein dairy cattle based on pedigree and SNP data prior and after genomic selection
Genetic diversity has become an urgent matter not only in small local breeds but also in
more specialized ones. While the use of genomic data in livestock breeding programs …
more specialized ones. While the use of genomic data in livestock breeding programs …
Genetic diversity and genomic signatures of selection among cattle breeds from Siberia, eastern and northern Europe
Domestication in the near eastern region had a major impact on the gene pool of humpless
taurine cattle (Bos taurus). As a result of subsequent natural and artificial selection …
taurine cattle (Bos taurus). As a result of subsequent natural and artificial selection …
Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle
H Pausch, H Schwarzenbacher, J Burgstaller… - BMC genomics, 2015 - Springer
Background Cattle breeding populations are susceptible to the propagation of recessive
diseases. Individual sires generate tens of thousands of progeny via artificial insemination …
diseases. Individual sires generate tens of thousands of progeny via artificial insemination …
Inferring demography from runs of homozygosity in whole-genome sequence, with correction for sequence errors
Whole-genome sequence is potentially the richest source of genetic data for inferring
ancestral demography. However, full sequence also presents significant challenges to fully …
ancestral demography. However, full sequence also presents significant challenges to fully …