Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

AM Sayed, AR Khattab, AM AboulMagd, HM Hassan… - RSC …, 2020 - pubs.rsc.org
The novel Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is a potential
factor for fatal illness and a tremendous concern for global public health. The COVID-19 …

Kaempferol: A review of current evidence of its antiviral potential

A Periferakis, AT Periferakis, L Troumpata… - International Journal of …, 2023 - mdpi.com
Kaempferol and its derivatives are flavonoids found in various plants, and a considerable
number of these have been used in various medical applications worldwide. Kaempferol …

Natural biflavonoids as potential therapeutic agents against microbial diseases

JC Menezes, VR Campos - Science of The Total Environment, 2021 - Elsevier
Microbes broadly constitute several organisms like viruses, protozoa, bacteria, and fungi
present in our biosphere. Fast-paced environmental changes have influenced contact of …

Current status of chikungunya in India

… Consortia (TRC) for Chikungunya Virus in … - Frontiers in …, 2021 - frontiersin.org
Chikungunya fever (CHIKF) is an arbovirus disease caused by chikungunya virus (CHIKV),
an alphavirus of Togaviridae family. Transmission follows a human-mosquito-human cycle …

[HTML][HTML] Repurposing potential of rimantadine hydrochloride and development of a promising platinum (II)-rimantadine metallodrug for the treatment of Chikungunya …

IA Santos, AK dos Santos Pereira, M Guevara-Vega… - Acta Tropica, 2022 - Elsevier
Most of the patients infected with Chikungunya virus (CHIKV) develop chronic
manifestations characterized by pain and deformity in joints, impacting their quality of life …

[HTML][HTML] Development and application of treatment for Chikungunya fever

EM Millsapps, EC Underwood… - Research and Reports in …, 2022 - ncbi.nlm.nih.gov
The development and application of treatment for Chikungunya fever (CHIKF) remains
complicated as there is no current standard treatment and many barriers to research exist …

Triphenylphosphine gold (I) derivatives promote antiviral effects against the Chikungunya virus

RL Aires, IA Santos, JV Fontes, FRG Bergamini… - Metallomics, 2022 - academic.oup.com
Herein a systematic series of four [AuLL'] n+ n= 0,+ 1 complexes, where L= 1, 3-bis (mesityl)
imidazole-2-ylidene (IMes), or triphenylphosphine (PPh3), and L'= chloride, or 4 …

[HTML][HTML] Identification and evaluation of antiviral potential of thymoquinone, a natural compound targeting Chikungunya virus capsid protein

R Kumar, S Nehul, A Singh, S Tomar - Virology, 2021 - Elsevier
Capsid protein (CP) of Chikungunya virus (CHIKV) is a multifunctional protein with a
conserved hydrophobic pocket that plays a crucial role in the capsid assembly and virus …

Alphaviruses: Host pathogenesis, immune response, and vaccine & treatment updates

I Guerrero-Arguero… - Journal of General …, 2021 - microbiologyresearch.org
Human pathogens belonging to the Alphavirus genus, in the Togaviridae family, are
transmitted primarily by mosquitoes. The signs and symptoms associated with these viruses …

Synthesis, spectroscopic characterization and in vitro antibacterial and antiviral activities of novel silver (I) complexes with mafenide and ethyl-mafenide

PG Esquezaro, CM Manzano, DH Nakahata… - Journal of Molecular …, 2021 - Elsevier
Two novel silver (I) complexes with the antibacterial sulfa drugs mafenide (Maf) and ethyl-
mafenide (eMaf) are presented in this article. Elemental analysis indicated the 1: 1 metal …