A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia
Acute myeloid leukemia (AML) is an extremely heterogeneous disease defined by the clonal
growth of myeloblasts/promyelocytes not only in the bone marrow but also in peripheral …
growth of myeloblasts/promyelocytes not only in the bone marrow but also in peripheral …
Magnetotactic Bacteria and Magnetosomes as Smart Drug Delivery Systems: A New Weapon on the Battlefield with Cancer?
D Kuzajewska, A Wszołek, W Żwierełło, L Kirczuk… - Biology, 2020 - mdpi.com
An important direction of research in increasing the effectiveness of cancer therapies is the
design of effective drug distribution systems in the body. The development of the new …
design of effective drug distribution systems in the body. The development of the new …
[HTML][HTML] Nucleoside-based anticancer drugs: Mechanism of action and drug resistance
Nucleoside-based drugs, recognized as purine or pyrimidine analogs, have been potent
therapeutic agents since their introduction in 1950, deployed widely in the treatment of …
therapeutic agents since their introduction in 1950, deployed widely in the treatment of …
Quantum chemical study of 2-hydroxypropyl-β-cyclodextrin and genipin-crosslinked chitosan nanocarriers functionalized with cytarabine anticancer drug
Drug delivery systems based on ring-like nanocarriers such as 2-hydroxypropyl-β-
cyclodextrin (HP-β-CD) and genipin-crosslinked chitosan (GCS) are increasingly used in the …
cyclodextrin (HP-β-CD) and genipin-crosslinked chitosan (GCS) are increasingly used in the …
CI codoped porous g-C3N4 for superior photocatalytic hydrogen evolution
C Yang, W Teng, Y Song, Y Cui - Chinese Journal of Catalysis, 2018 - Elsevier
Porous CI codoped carbon nitride materials were synthesized by in-situ codoping with
iodized ionic liquid followed by post-thermal treatment in air. The effects of doping content of …
iodized ionic liquid followed by post-thermal treatment in air. The effects of doping content of …
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax
K Fooks, G Galicia-Vazquez, V Gife… - Journal of Experimental …, 2022 - Springer
Background Acute myeloid leukemia (AML) is an aggressive hematological cancer resulting
from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of …
from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of …
Curcumin and tetrahydrocurcumin induce cell death in Ara‐C‐resistant acute myeloid leukemia
YH Tseng, SS Chiou, JP Weng… - Phytotherapy Research, 2019 - Wiley Online Library
Most anticancer agents induce cancer cell death; however, multidrug‐resistant cancers often
lead to treatment failure. The effective use of curcumin as an anticancer agent has been …
lead to treatment failure. The effective use of curcumin as an anticancer agent has been …
Proteasome inhibitors interrupt the activation of Non-Canonical NF-κB signaling pathway and induce cell apoptosis in Cytarabine-Resistant HL60 cells
Over half of older patients with acute myeloid leukemia (AML) do not respond to cytotoxic
chemotherapy, and most responders relapse because of drug resistance. Cytarabine is the …
chemotherapy, and most responders relapse because of drug resistance. Cytarabine is the …
Method for quantification of ribonucleotides and deoxyribonucleotides in human cells using (trimethylsilyl) diazomethane derivatization followed by liquid …
Investigation into intracellular ribonucleotides (RNs) and deoxyribonucleotides (dRNs) is
important for studies of the mechanism of many biological processes, such as RNA and DNA …
important for studies of the mechanism of many biological processes, such as RNA and DNA …
Magnetosomes as potential nanocarriers for cancer treatment
R Alsharedeh, N Alshraiedeh, AA Aljabali… - Current Drug …, 2024 - benthamdirect.com
Magnetotactic bacteria (MTBs) and their organelles, magnetosomes, are intriguing options
that might fulfill the criteria of using bacterial magnetosomes (BMs). The ferromagnetic …
that might fulfill the criteria of using bacterial magnetosomes (BMs). The ferromagnetic …