A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia

A Kirtonia, G Pandya, G Sethi, AK Pandey… - Journal of molecular …, 2020 - Springer
Acute myeloid leukemia (AML) is an extremely heterogeneous disease defined by the clonal
growth of myeloblasts/promyelocytes not only in the bone marrow but also in peripheral …

Magnetotactic Bacteria and Magnetosomes as Smart Drug Delivery Systems: A New Weapon on the Battlefield with Cancer?

D Kuzajewska, A Wszołek, W Żwierełło, L Kirczuk… - Biology, 2020 - mdpi.com
An important direction of research in increasing the effectiveness of cancer therapies is the
design of effective drug distribution systems in the body. The development of the new …

[HTML][HTML] Nucleoside-based anticancer drugs: Mechanism of action and drug resistance

L Hruba, V Das, M Hajduch, P Dzubak - Biochemical Pharmacology, 2023 - Elsevier
Nucleoside-based drugs, recognized as purine or pyrimidine analogs, have been potent
therapeutic agents since their introduction in 1950, deployed widely in the treatment of …

Quantum chemical study of 2-hydroxypropyl-β-cyclodextrin and genipin-crosslinked chitosan nanocarriers functionalized with cytarabine anticancer drug

A Rezaei, SH Vahidi, M Nasrabadi… - Journal of Molecular …, 2022 - Elsevier
Drug delivery systems based on ring-like nanocarriers such as 2-hydroxypropyl-β-
cyclodextrin (HP-β-CD) and genipin-crosslinked chitosan (GCS) are increasingly used in the …

CI codoped porous g-C3N4 for superior photocatalytic hydrogen evolution

C Yang, W Teng, Y Song, Y Cui - Chinese Journal of Catalysis, 2018 - Elsevier
Porous CI codoped carbon nitride materials were synthesized by in-situ codoping with
iodized ionic liquid followed by post-thermal treatment in air. The effects of doping content of …

EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax

K Fooks, G Galicia-Vazquez, V Gife… - Journal of Experimental …, 2022 - Springer
Background Acute myeloid leukemia (AML) is an aggressive hematological cancer resulting
from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of …

Curcumin and tetrahydrocurcumin induce cell death in Ara‐C‐resistant acute myeloid leukemia

YH Tseng, SS Chiou, JP Weng… - Phytotherapy Research, 2019 - Wiley Online Library
Most anticancer agents induce cancer cell death; however, multidrug‐resistant cancers often
lead to treatment failure. The effective use of curcumin as an anticancer agent has been …

Proteasome inhibitors interrupt the activation of Non-Canonical NF-κB signaling pathway and induce cell apoptosis in Cytarabine-Resistant HL60 cells

SY Wang, YH Shih, TM Shieh, YH Tseng - International Journal of …, 2021 - mdpi.com
Over half of older patients with acute myeloid leukemia (AML) do not respond to cytotoxic
chemotherapy, and most responders relapse because of drug resistance. Cytarabine is the …

Method for quantification of ribonucleotides and deoxyribonucleotides in human cells using (trimethylsilyl) diazomethane derivatization followed by liquid …

Z Li, HX Zhang, Y Li, CWK Lam, CY Wang… - Analytical …, 2018 - ACS Publications
Investigation into intracellular ribonucleotides (RNs) and deoxyribonucleotides (dRNs) is
important for studies of the mechanism of many biological processes, such as RNA and DNA …

Magnetosomes as potential nanocarriers for cancer treatment

R Alsharedeh, N Alshraiedeh, AA Aljabali… - Current Drug …, 2024 - benthamdirect.com
Magnetotactic bacteria (MTBs) and their organelles, magnetosomes, are intriguing options
that might fulfill the criteria of using bacterial magnetosomes (BMs). The ferromagnetic …