Beyond casual resemblance: rigorous frameworks for comparing regeneration across species

M Srivastava - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
The majority of animal phyla have species that can regenerate. Comparing regeneration
across animals can reconstruct the molecular and cellular evolutionary history of this …

Animal regeneration in the era of transcriptomics

L Bideau, P Kerner, J Hui, M Vervoort… - Cellular and Molecular …, 2021 - Springer
Animal regeneration, the ability to restore a lost body part, is a process that has fascinated
scientists for centuries. In this review, we first present what regeneration is and how it relates …

Wnt/β-catenin signalling is required for pole-specific chromatin remodeling during planarian regeneration

E Pascual-Carreras, M Marín-Barba… - Nature …, 2023 - nature.com
For successful regeneration, the identity of the missing tissue must be specified according to
the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this …

Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling

A Tursch, N Bartsch, M Mercker… - Proceedings of the …, 2022 - National Acad Sciences
Hydra's almost unlimited regenerative potential is based on Wnt signaling, but so far it is
unknown how the injury stimulus is transmitted to discrete patterning fates in head and foot …

Acoel single-cell atlas reveals expression dynamics and heterogeneity of adult pluripotent stem cells

RE Hulett, JO Kimura, DM Bolaños, YJ Luo… - Nature …, 2023 - nature.com
Adult pluripotent stem cell (aPSC) populations underlie whole-body regeneration in many
distantly-related animal lineages, but how the underlying cellular and molecular …

A wound-induced differentiation trajectory for neurons

RE Hulett, C Rivera-López, AR Gehrke… - Proceedings of the …, 2024 - pnas.org
Animals capable of whole-body regeneration can replace any missing cell type and
regenerate fully functional new organs, including new brains, de novo. The regeneration of a …

Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra

JF Cazet, A Cho, CE Juliano - Elife, 2021 - elifesciences.org
During whole-body regeneration, a bisection injury can trigger two different types of
regeneration. To understand the transcriptional regulation underlying this adaptive …

Hif1α and Wnt are required for posterior gene expression during Xenopus tropicalis tail regeneration

JH Patel, PA Schattinger, EE Takayoshi, AE Wills - Developmental biology, 2022 - Elsevier
Regeneration of complex tissues is initiated by an injury-induced stress response,
eventually leading to activation of developmental signaling pathways such as Wnt signaling …

Whole-Body Regeneration in the Lobate Ctenophore Mnemiopsis leidyi

A Edgar, DG Mitchell, MQ Martindale - Genes, 2021 - mdpi.com
Ctenophores (aka comb jellies) are one of the earliest branching extant metazoan phyla.
Adult regenerative ability varies greatly within the group, with platyctenes undergoing both …

Cnidofest 2022: hot topics in cnidarian research

JM Gahan, P Cartwright, ML Nicotra, CE Schnitzler… - EvoDevo, 2023 - Springer
Abstract The second annual Cnidarian Model Systems Meeting, aka “Cnidofest”, took place
in Davis, California from 7 to 10th of September, 2022. The meeting brought together …