How softness matters in soft nanogels and nanogel assemblies
Softness plays a key role in determining the macroscopic properties of colloidal systems,
from synthetic nanogels to biological macromolecules, from viruses to star polymers …
from synthetic nanogels to biological macromolecules, from viruses to star polymers …
Insight into cellular uptake and intracellular trafficking of nanoparticles
P Foroozandeh, AA Aziz - Nanoscale research letters, 2018 - Springer
Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …
defining new technological platforms. This is perhaps even more evident in the field of …
[HTML][HTML] Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell
D Manzanares, V Ceña - Pharmaceutics, 2020 - mdpi.com
Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …
Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein AI in corona formation
M Li, X Jin, T Liu, F Fan, F Gao, S Chai… - Nature communications, 2022 - nature.com
Nanoparticle elasticity is crucial in nanoparticles' physiological fate, but how this occurs is
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …
Role of nanoparticle mechanical properties in cancer drug delivery
The physicochemical properties of nanoparticles play critical roles in regulating nano-bio
interactions. Whereas the effects of the size, shape, and surface charge of nanoparticles on …
interactions. Whereas the effects of the size, shape, and surface charge of nanoparticles on …
Understanding the extracellular vesicle surface for clinical molecular biology
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …
Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles
Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …
delivery of anticancer drugs. The most important causes of failure in clinical translation of …
Nanoparticle elasticity directs tumor uptake
To date, the role of elasticity in drug delivery remains elusive due to the inability to measure
microscale mechanics and alter rheology without affecting chemistry. Herein, we describe …
microscale mechanics and alter rheology without affecting chemistry. Herein, we describe …
Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation
Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …
molecules with a capability to respond to external stimuli that can be used for a multitude of …
Nanoparticles and innate immunity: new perspectives on host defence
The innate immune system provides the first line of defence against foreign microbes and
particulate materials. Engineered nanoparticles can interact with the immune system in …
particulate materials. Engineered nanoparticles can interact with the immune system in …