Objective: Cryptococcal meningitis is one of the most important HIV-related opportunistic
infections, especially in the developing world. In order to help develop global strategies and …

Background The prognosis, specifically the case fatality and duration, of untreated
tuberculosis is important as many patients are not correctly diagnosed and therefore receive …

Background In sub-Saharan Africa, the burden of human immunodeficiency virus (HIV)–
associated tuberculosis is high. We conducted a trial with a 2-by-2 factorial design to assess …

The incidence of invasive mycoses is increasing, especially among patients who are
immunocompromised or hospitalized with serious underlying diseases. Such infections may …

Background The increasing global burden of tuberculosis (TB) is linked to human
immunodeficiency virus (HIV) infection. Methods We reviewed data from notifications of TB …

Cryptococcal meningitis is a common opportunistic infection in AIDS patients, particularly in
Southeast Asia and Africa. Cases also occur in patients with other forms of …

Background Tuberculosis is epidemic among workers in South African gold mines. We
evaluated an intervention to interrupt tuberculosis transmission by means of mass screening …

The fungus Cryptococcus neoformans is a leading cause of mortality and morbidity among
HIV-infected individuals. We utilized the completed genome sequence and optimized …

To examine trends in the incidence and epidemiology of cryptococcosis, active, population-
based surveillance was conducted during 1992–2000 in 2 areas of the United States (the …

Background Although antiretroviral therapy (ART) improves survival in persons with
cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution …